2-[(2R)-5,6-dimethyl-1,2,3,4-tetrahydronaphthalen-2-yl]propan-2-ol

Base Information

Chemical Name:2-[(2R)-5,6-dimethyl-1,2,3,4-tetrahydronaphthalen-2-yl]propan-2-ol
CAS No.:87797-89-5
Molecular Formula:C₁₅H₂₂O
Molecular Weight:218.339
Hs Code.:
DSSTox Substance ID:DTXSID201167316
Nikkaji Number:J38.795I
Wikidata:Q105215510
Mol file:87797-89-5.mol

Synonyms:87797-89-5;DTXSID201167316

Suppliers and Price of 2-[(2R)-5,6-dimethyl-1,2,3,4-tetrahydronaphthalen-2-yl]propan-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-[(2R)-5,6-dimethyl-1,2,3,4-tetrahydronaphthalen-2-yl]propan-2-ol

Chemical Property:

XLogP3:3.5
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:218.167065321
Heavy Atom Count:16
Complexity:246

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC1=C(C2=C(CC(CC2)C(C)(C)O)C=C1)C
Isomeric SMILES:CC1=C(C2=C(C[C@@H](CC2)C(C)(C)O)C=C1)C

Technology Process of 2-[(2R)-5,6-dimethyl-1,2,3,4-tetrahydronaphthalen-2-yl]propan-2-ol

There total 5 articles about 2-[(2R)-5,6-dimethyl-1,2,3,4-tetrahydronaphthalen-2-yl]propan-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

: 917-64-6
methyl magnesium iodide

: 116987-92-9
ethyl 5,6-dimethyl-1,2,3,4-tetrahydro-2-naphthoate

: 176435-28-2,87797-89-5
(+/-)-5,6-dimethyl-2-(2-hydroxyisopropyl)tetralin

Guidance literature:: In diethyl ether; for 10h; Heating; ether, reflux, 10 h;

Reference yield: 78.1%

: 917-54-4
methyllithium

: 332075-10-2
5,6-dimethyl-1,2,3,4-tetrahydro-2-naphthoic acid

: 176435-28-2,87797-89-5
(+/-)-5,6-dimethyl-2-(2-hydroxyisopropyl)tetralin

Guidance literature:: In diethyl ether; at 20 ℃;

Reference yield:

: 13621-30-2
4-(2,3-dimethylphenyl)butanoic acid

: 176435-28-2,87797-89-5
(+/-)-5,6-dimethyl-2-(2-hydroxyisopropyl)tetralin

Guidance literature:: Multi-step reaction with 4 steps

1: 80percent sulphuric acid

2: 91.5 percent / NaH / benzene / 10 h / Heating

3: 63.6 percent / 1) dry HCl gas, 2) activated Zn dust / diethyl ether / 3 h / 0 °C

4: 85 percent / diethyl ether / 10 h / Heating; ether, reflux, 10 h

With hydrogenchloride; sulfuric acid; sodium hydride; zinc; In diethyl ether; benzene;