2,2-Dioxide-1,2,3-oxathiazolidine

Base Information

• Chemical Name: 2,2-Dioxide-1,2,3-oxathiazolidine
• CAS No.: 19044-42-9
• Molecular Formula: C2H5NO3S
• Molecular Weight: 123.13100
• Mol file: 19044-42-9.mol

Synonyms:2,2-DIOXIDE-1,2,3-OXATHIAZOLIDINE;1,2,3-Oxathiazolidine,2,2-dioxide;

Chemical Property of 2,2-Dioxide-1,2,3-oxathiazolidine

Chemical Property:

• PSA: 63.78000
• LogP: 0.26060

Purity/Quality:

97% ^*data from raw suppliers

2,2-Dioxide-1,2,3-oxathiazolidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,2-Dioxide-1,2,3-oxathiazolidine is a useful reagent in the preparation of thiophene analogs of viloxazine which are potential antidepressant drugs.

Technology Process of 2,2-Dioxide-1,2,3-oxathiazolidine

There total 1 articles about 2,2-Dioxide-1,2,3-oxathiazolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

2,2-dioxo-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester (459817-82-4) → [1,2,3]-oxathiazolidine-2,2-dioxide (19044-42-9)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 20 ℃; for 1h;

DOI:10.1016/j.bmcl.2008.09.034

Reference yield: 61.0%

[1,2,3]-oxathiazolidine-2,2-dioxide (19044-42-9) + (2S,4S)-2-mesyloxymethyl-4-tritylthio-1-(allyloxycarbonyl)pyrrolidine (137934-48-6) → (C6H5)3CSCH2CHCH2OCOC4H6NCH2NC2H4SO3

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 5h;

DOI:10.1016/j.ejmech.2007.02.001

Reference yield: 47.0%

2-(4-Phenyl-thiophen-3-yloxymethyl)-oxirane (177974-81-1) + [1,2,3]-oxathiazolidine-2,2-dioxide (19044-42-9) → 2-(4-phenyl-thiophen-3-yloxymethyl)-morpholine

Guidance literature:

With sodium hydroxide; In N,N-dimethyl-formamide; at 50 - 55 ℃; for 1h;

DOI:10.1016/S0968-0896(99)00070-X

upstream raw materials:

2,2-dioxo-[1,2,3]oxathiazolidine-3-carboxylic acid tert-butyl ester

Downstream raw materials:

C₈H₇FN₂O₅S

3-Methyl-[1,2,3]oxathiazolidine 2,2-dioxide

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