2H-1,3-Benzothiazine-2,4(3H)-dione, 3-(2-(diethylamino)ethyl)-, hydrochloride

Base Information

• Chemical Name: 2H-1,3-Benzothiazine-2,4(3H)-dione, 3-(2-(diethylamino)ethyl)-, hydrochloride
• CAS No.: 81735-46-8
• Molecular Formula: C₁₄H₁₈N₂O₂S*ClH
• Molecular Weight: 314.836
• DSSTox Substance ID: DTXSID30231305
• Mol file: 81735-46-8.mol

Synonyms:2H-1,3-Benzothiazine-2,4(3H)-dione, 3-(2-(diethylamino)ethyl)-, hydrochloride;3-(2-(Diethylamino)ethyl)-2H-1,3-benzothiazine-2,4(3H)-dione hydrochloride;3-Diethylaminoethyl-3,4-dihydro-1,3-benzothiazine-2,4-dione, hydrochloride;81735-46-8;DTXSID30231305;LS-40560

Chemical Property of 2H-1,3-Benzothiazine-2,4(3H)-dione, 3-(2-(diethylamino)ethyl)-, hydrochloride

Chemical Property:

• Vapor Pressure: 3.16E-07mmHg at 25°C
• Boiling Point: 418.9°Cat760mmHg
• Flash Point: 207.2°C
• Density: g/cm³
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 5
• Exact Mass: 314.0855767
• Heavy Atom Count: 20
• Complexity: 344

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCN(CC)CCN1C(=O)C2=CC=CC=C2SC1=O.Cl

Technology Process of 2H-1,3-Benzothiazine-2,4(3H)-dione, 3-(2-(diethylamino)ethyl)-, hydrochloride

There total 1 articles about 2H-1,3-Benzothiazine-2,4(3H)-dione, 3-(2-(diethylamino)ethyl)-, hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

2-(diethylamino)ethyl chloride (100-35-6) + 4H-2,3-dihydro-1,3-benzothiazine-2,4-dione (10512-65-9) → 3-(2-Diethylamino-ethyl)-benzo[e][1,3]thiazine-2,4-dione; hydrochloride (81735-46-8)

Guidance literature:

With sodium hydride; In N,N,N,N,N,N-hexamethylphosphoric triamide;

DOI:10.1007/BF00762029

upstream raw materials:

2-(diethylamino)ethyl chloride

4H-2,3-dihydro-1,3-benzothiazine-2,4-dione