Benzenesulfonamide, N-[2-[(3-hydroxypropyl)amino]ethyl]-2-nitro-

Base Information

Chemical Name:Benzenesulfonamide, N-[2-[(3-hydroxypropyl)amino]ethyl]-2-nitro-
CAS No.:192379-55-8
Molecular Formula:C11H17N3O5S
Molecular Weight:303.339
Hs Code.:
DSSTox Substance ID:DTXSID30444852
Mol file:192379-55-8.mol

Synonyms:Benzenesulfonamide, N-[2-[(3-hydroxypropyl)amino]ethyl]-2-nitro-;192379-55-8;DTXSID30444852

Suppliers and Price of Benzenesulfonamide, N-[2-[(3-hydroxypropyl)amino]ethyl]-2-nitro-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Benzenesulfonamide, N-[2-[(3-hydroxypropyl)amino]ethyl]-2-nitro-

Chemical Property:

XLogP3:0
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:8
Exact Mass:303.08889182
Heavy Atom Count:20
Complexity:390

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)[N+](=O)[O-])S(=O)(=O)NCCNCCCO

Technology Process of Benzenesulfonamide, N-[2-[(3-hydroxypropyl)amino]ethyl]-2-nitro-

There total 1 articles about Benzenesulfonamide, N-[2-[(3-hydroxypropyl)amino]ethyl]-2-nitro- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 57.0%

: 56344-32-2
N-(3-hydroxypropyl)ethylenediamine

: 1694-92-4
2-Nitrobenzenesulfonyl chloride

: 192379-55-8
N-[2-(3-Hydroxy-propylamino)-ethyl]-2-nitro-benzenesulfonamide

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 1h;
DOI:10.1021/jo970535j

Reference yield: 93.0%

: 24424-99-5
di-tert-butyl dicarbonate

: 192379-55-8
N-[2-(3-Hydroxy-propylamino)-ethyl]-2-nitro-benzenesulfonamide

: 192379-57-0
(3-Hydroxy-propyl)-[2-(2-nitro-benzenesulfonylamino)-ethyl]-carbamic acid tert-butyl ester

Guidance literature:: With triethylamine; In tetrahydrofuran; 0 deg C, 20 min, rt, 24 h;
DOI:10.1021/jo970535j

Reference yield:

: 192379-55-8
N-[2-(3-Hydroxy-propylamino)-ethyl]-2-nitro-benzenesulfonamide

: 192379-50-3
{2-[(6-Aminomethyl-pyridin-2-ylmethyl)-(2-nitro-benzenesulfonyl)-amino]-ethyl}-(3-hydroxy-propyl)-carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / Et₃N / tetrahydrofuran / 0 deg C, 20 min, rt, 24 h

2: 88 percent / K₂CO₃ / dimethylformamide / 24 h / Ambient temperature

3: 77 percent / NH₂NH₂ / CH₂Cl₂ / 24 h / Ambient temperature

With potassium carbonate; triethylamine; hydrazine; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jo970535j