Methanone, [2-amino-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl](4-bromophen yl)-

Base Information

• Chemical Name: Methanone, [2-amino-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl](4-bromophen yl)-
• CAS No.: 192435-56-6
• Molecular Formula: C23H29BrN2O2
• Molecular Weight: 445.399
• Mol file: 192435-56-6.mol

Synonyms:

Chemical Property of Methanone, [2-amino-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl](4-bromophen yl)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Methanone, [2-amino-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl](4-bromophen yl)-

There total 2 articles about Methanone, [2-amino-4-[[6-(methyl-2-propenylamino)hexyl]oxy]phenyl](4-bromophen yl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

[4-[6-(allylmethylamino)hexyloxy]-2-(4-methoxybenzylamino)phenyl](4-bromophenyl)methanone (192437-69-7) → [2-amino-4-[6-(allylmethylamino)hexyloxy]phenyl](4-bromophenyl)methanone (192435-56-6)

Guidance literature:

With trifluoroacetic acid; at 20 ℃; for 45h;

DOI:10.1021/jm021120f

Reference yield:

[4-[6-(allyl-methyl-amino)-hexyloxy]-2-fluoro-phenyl]-(4-bromo-phenyl)-methanone (161582-11-2) → [2-amino-4-[6-(allylmethylamino)hexyloxy]phenyl](4-bromophenyl)methanone (192435-56-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 79 percent / K₂CO₃ / toluene / 23 h / Heating

2: 96 percent / TFA / 45 h / 20 °C

With potassium carbonate; trifluoroacetic acid; In toluene;

DOI:10.1021/jm021120f

Reference yield:

[2-amino-4-[6-(allylmethylamino)hexyloxy]phenyl](4-bromophenyl)methanone (192435-56-6) → N-[5-[6-(allyl-methyl-amino)-hexyloxy]-2-(4-bromo-benzoyl)-phenyl]-formamide

Guidance literature:

With formamide; In formic acid;

upstream raw materials:

[4-[6-(allylmethylamino)hexyloxy]-2-(4-methoxybenzylamino)phenyl](4-bromophenyl)methanone

[4-[6-(allyl-methyl-amino)-hexyloxy]-2-fluoro-phenyl]-(4-bromo-phenyl)-methanone

Refernces