Glycine, N-[(4-fluoro-3-nitrophenyl)acetyl]-

Base Information

Chemical Name:Glycine, N-[(4-fluoro-3-nitrophenyl)acetyl]-
CAS No.:192508-38-6
Molecular Formula:C10H9FN2O5
Molecular Weight:256.19
Hs Code.:
DSSTox Substance ID:DTXSID80453550
Nikkaji Number:J840.626J
Wikidata:Q82274709
Mol file:192508-38-6.mol

Synonyms:Glycine, N-[(4-fluoro-3-nitrophenyl)acetyl]-;192508-38-6;DTXSID80453550;N-(alpha-Oxo-3-nitro-4-fluorophenethyl)glycine

Suppliers and Price of Glycine, N-[(4-fluoro-3-nitrophenyl)acetyl]-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Glycine, N-[(4-fluoro-3-nitrophenyl)acetyl]-

Chemical Property:

XLogP3:0.7
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:4
Exact Mass:256.04954955
Heavy Atom Count:18
Complexity:344

Purity/Quality:: 99.90% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1CC(=O)NCC(=O)O)[N+](=O)[O-])F

Technology Process of Glycine, N-[(4-fluoro-3-nitrophenyl)acetyl]-

There total 4 articles about Glycine, N-[(4-fluoro-3-nitrophenyl)acetyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 192508-37-5
<2-(4-fluoro-3-nitrophenyl)-acetylamino>-acetic acid methyl ester

: 192508-38-6
<2-(4-fluoro-3-nitrophenyl)-acetylamino>-acetic acid

Guidance literature:: With potassium carbonate; In methanol;
DOI:10.1016/S0040-4039(97)00941-6

Reference yield:

: 192508-36-4
2-(4-fluoro-3-nitrophenyl)acetic acid

: 192508-38-6
<2-(4-fluoro-3-nitrophenyl)-acetylamino>-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 93 percent / NEt₃, DCC / dimethylformamide / 5 h / Ambient temperature

2: 94 percent / K₂CO₃ / methanol; H₂O / 5 h / Ambient temperature

With potassium carbonate; triethylamine; dicyclohexyl-carbodiimide; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(99)00171-4

Reference yield:

: 157662-77-6
2-(4-fluoro-3-nitrophenyl)acetonitrile

: 192508-38-6
<2-(4-fluoro-3-nitrophenyl)-acetylamino>-acetic acid

Guidance literature:: Multi-step reaction with 4 steps

1: 85 percent / HCl / 4 h / 0 °C

2: 98 percent / aq. NaOH / methanol / 2 h / Ambient temperature

3: 93 percent / NEt₃, DCC / dimethylformamide / 5 h / Ambient temperature

4: 94 percent / K₂CO₃ / methanol; H₂O / 5 h / Ambient temperature

With hydrogenchloride; sodium hydroxide; potassium carbonate; triethylamine; dicyclohexyl-carbodiimide; In methanol; water; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(99)00171-4