157662-77-6

Basic information

• Product Name: (4-FLUORO-3-NITROPHENYL)ACETONITRILE
• Synonyms: (4-FLUORO-3-NITROPHENYL)ACETONITRILE;2-(4-FLUORO-3-NITROPHENYL)ACETONITRILE
• CAS NO: 157662-77-6
• Molecular Formula: C₈H₅FN₂O₂
• Molecular Weight: 180.14
• Product Categories: Aromatic Nitriles
• Mol File: 157662-77-6.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 349.982°C at 760 mmHg
• Flash Point: 165.464°C
• Appearance: /
• Density: 1.368g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.555
• Storage Temp.: Sealed in dry,Room Temperature
• CAS DataBase Reference: (4-FLUORO-3-NITROPHENYL)ACETONITRILE(CAS DataBase Reference)
• NIST Chemistry Reference: (4-FLUORO-3-NITROPHENYL)ACETONITRILE(157662-77-6)
• EPA Substance Registry System: (4-FLUORO-3-NITROPHENYL)ACETONITRILE(157662-77-6)

Safety Data

• Hazardous Substances Data: 157662-77-6(Hazardous Substances Data)

Usage

Application

(4-Fluoro-3-Nitrophenyl)Acetonitrile is a useful research chemical compound.

InChI:InChI=1/C8H5FN2O2/c9-7-2-1-6(3-4-10)5-8(7)11(12)13/h1-2,5H,3H2

Upstream product

• 15017-52-4 4-(bromomethyl)-1-fluoro-2-nitrobenzene 
• 459-57-4 4-fluorobenzaldehyde 
• 446-11-7 4-fluoro-3-nitrotoluene 
• 13435-20-6 tetraethylammoniumcyanide 
• 459-22-3 4-fluorophenylacetonitrile 
• 773837-37-9 sodium cyanide 
• 20274-70-8 4-(chloromethyl)-1-fluoro-2-nitrobenzene 
• 42564-51-2 4-fluoro-3-nitrobenzaldehyde 
• 20274-69-5 (4-fluoro-3-nitrophenyl)methanol 

Downstream Products

• 1304495-14-4 C₁₅H₁₂N₂O₄ 
• 788824-56-6 N-t-butoxycarbonyl-3-iodothyronamine 
• 788824-64-6 3-Iodothyronamine hydrochloride 
• 1304495-16-6 C₁₄H₁₀INO₂ 
• 1304495-15-5 C₁₅H₁₄N₂O₂ 
• 100866-04-4 [3-iodo-4-(4-methoxy-phenoxy)-phenyl]-acetonitrile 
• 157662-70-9 (2R)-2-<(tert-Butyloxycarbonyl)amino>-N-(4-fluoro-3-nitrophenethyl)-p-methoxyphenylacetamide 
• 160877-33-8 (2R)-2-<(tert-Butyloxycarbonyl)amino>-N-(4-fluoro-3-nitrophenethyl)-p-hydroxyphenylacetamide 
• 157662-69-6 2-<(tert-Butyloxycarbonyl)amino>-N-(4-fluoro-3-nitrophenethyl)acetamide 
• 226888-23-9 2-<(2R)-2-(4-fluoro-3-nitrophenyl)-acetylamino>-N-(3-isopropoxy-4-methoxybenzyl)-3-phenylpropionamide 
• 226888-40-0 2-<(2R)-2-(4-fluoro-3-nitrophenyl)-acetylamino>-N-(3-hydroxy-4-methoxybenzyl)-3-phenylpropionamide 

Relevant articles and documents

MODULATORS OF INDOLEAMINE 2,3-DIOXYGENASE

Provided are IDO inhibitor compounds of Formula (I) and pharmaceutically acceptable salts thereof, their pharmaceutical compositions, their methods of preparation, and methods for their use in the prevention and/or treatment of diseases such as chronic viral infection, chronic bacterial infections, cancer, sepsis or a neurological disorder.

A new efficient synthetic method for 3-iodothyronamine involving sonication and its potent hypothermic efficacy

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SNAr-Based Macrocyclization: An Application to the Synthesis of Vancomycin Family Models

The first examples of macrocyclization using the intramolecular SNAr reaction are reported.The method has allowed the efficient preparation of the elusive 16-membered macrocyclic COD and DOE rings related to vancomycin.The mild conditions used allow the incorporation of very racemization-prone amino acids, such as p-methoxyphenylglycine, into the peptide chain.After serving as an activator, the nitro group ortho to the diaryl ether linkage is converted either into a chlorine or a hydrogen atom, thus achieving the substitution pattern found in the vancomycin family of glycopeptides.When compound 20 was submitted to the same macrocyclization conditions, two atropisomers 21 and 22 were isolated and characterized.