Phenol, 2-methoxy-6-[[(2-methylphenyl)imino]methyl]-

Base Information

• Chemical Name: Phenol, 2-methoxy-6-[[(2-methylphenyl)imino]methyl]-
• CAS No.: 19264-42-7
• Molecular Formula: C15H15NO2
• Molecular Weight: 241.29
• Mol file: 19264-42-7.mol

Synonyms:

Chemical Property of Phenol, 2-methoxy-6-[[(2-methylphenyl)imino]methyl]-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Phenol, 2-methoxy-6-[[(2-methylphenyl)imino]methyl]-

There total 1 articles about Phenol, 2-methoxy-6-[[(2-methylphenyl)imino]methyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-methoxy-2-hydroxybenzaldehyde (148-53-8) + o-toluidine (95-53-4) → vanillinidene-2-methyl-1-aminobenzene (19264-42-7)

Guidance literature:

In methanol; for 6h; Reflux;

DOI:10.1515/mgmc-2017-0008

Reference yield: 75.0%

[tris(triphenylphosphine) ruthenium(III) trichloride] (30050-39-6,23311-38-8) + vanillinidene-2-methyl-1-aminobenzene (19264-42-7) → RuCl2(PPh3)2(2-O-3-OMe-C6H3CHNC6H4Me-2) (303089-83-0)

Guidance literature:

With Et₃N; In benzene; byproducts: Et3NHCl; Schiff base was added in equimolar. amt. to C6H6 soln. of Ru-complex, Et3N was added, reflux for 5 h; Et3NHCl was filtered off, soln. was concd., cooled to room temp., lightpetroleum (60-80 °C) was added, ppt. was filtered off, washed with light petroleum, recrystd. from CH2Cl2/light petroleum, dried in vac., elem. anal.;

DOI:10.1080/00945710009351833

Reference yield: 72.0%

[tris(triphenylarsine) ruthenium(III) tribromide] (63632-06-4,72747-40-1) + vanillinidene-2-methyl-1-aminobenzene (19264-42-7) → RuBr2(AsPh3)2(2-O-3-OMe-C6H3CHNC6H4Me-2) (303089-85-2)

Guidance literature:

With Et₃N; In benzene; byproducts: Et3NHCl; Schiff base was added in equimolar. amt. to C6H6 soln. of Ru-complex, Et3N was added, reflux for 5 h; Et3NHCl was filtered off, soln. was concd., cooled to room temp., lightpetroleum (60-80 °C) was added, ppt. was filtered off, washed with light petroleum, recrystd. from CH2Cl2/light petroleum, dried in vac., elem. anal.;

DOI:10.1080/00945710009351833

upstream raw materials:

3-methoxy-2-hydroxybenzaldehyde

o-toluidine

Downstream raw materials:

RuCl₂(PPh₃)2(2-O-3-OMe-C₆H₃CHNC₆H₄Me-2)

RuCl₂(AsPh₃)2(2-O-3-OMe-C₆H₃CHNC₆H₄Me-2)

RuBr₂(PPh₃)2(2-O-3-OMe-C₆H₃CHNC₆H₄Me-2)

RuBr₂(AsPh₃)2(2-O-3-OMe-C₆H₃CHNC₆H₄Me-2)