2-CarboxyMethoxyMethyl-piperidine-1-carboxylic acid tert-butyl ester

Base Information

Chemical Name:2-CarboxyMethoxyMethyl-piperidine-1-carboxylic acid tert-butyl ester
CAS No.:193086-00-9
Molecular Formula:C₁₃H₂₃NO₅
Molecular Weight:273.329
Hs Code.:2933399090
Mol file:193086-00-9.mol

Synonyms:2-Carboxymethoxymethyl-piperidine-1-carboxylic acid tert-butyl ester;

Suppliers and Price of 2-CarboxyMethoxyMethyl-piperidine-1-carboxylic acid tert-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Chemenu
2-(1-(tert-Butoxycarbonyl)piperidin-2-yl)-2-methoxyaceticacid 95%
1g
$ 839.00

Alichem
2-(1-(tert-Butoxycarbonyl)piperidin-2-yl)-2-methoxyaceticacid
1g
$ 722.00

Total 5 raw suppliers

Chemical Property of 2-CarboxyMethoxyMethyl-piperidine-1-carboxylic acid tert-butyl ester

Chemical Property:

PSA：76.07000
LogP:1.81510

Purity/Quality:

97% ^*data from raw suppliers

2-(1-(tert-Butoxycarbonyl)piperidin-2-yl)-2-methoxyaceticacid 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-CarboxyMethoxyMethyl-piperidine-1-carboxylic acid tert-butyl ester

There total 4 articles about 2-CarboxyMethoxyMethyl-piperidine-1-carboxylic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 1018826-49-7
tert-butyl 2-((2-tert-butoxy-2-oxoethoxy)methyl)piperidine-1-carboxylate

: 193086-00-9
((1-(tert-butoxycarbonyl)piperidin-2-yl)methoxy)acetic acid

Guidance literature:: tert-butyl 2-((2-tert-butoxy-2-oxoethoxy)methyl)piperidine-1-carboxylate; With sodium hydroxide; water; In tetrahydrofuran; at 90 ℃; for 3h;

With hydrogenchloride; In tetrahydrofuran; water; at 20 ℃; pH=2;

Reference yield:

: 157634-00-9
tert-butyl 2-(hydroxymethyl)piperidine-1-carboxylate

: 193086-00-9
((1-(tert-butoxycarbonyl)piperidin-2-yl)methoxy)acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: [Rh₂(OAc)4] / 1,2-dichloro-ethane / Heating

2: LiOH / methanol; H₂O

With lithium hydroxide; dirhodium tetraacetate; In methanol; water; 1,2-dichloro-ethane; 1: Etherification / 2: Hydrolysis;
DOI:10.1016/S0223-5234(99)80086-5