2,3-Dimethylquinoxaline 1,4-dioxide

Base Information

• Chemical Name: 2,3-Dimethylquinoxaline 1,4-dioxide
• CAS No.: 5432-74-6
• Molecular Formula: C10H10 N2 O2
• Molecular Weight: 190.202
• Hs Code.: 2933990090
• NSC Number: 47511,21658
• DSSTox Substance ID: DTXSID30202691
• Nikkaji Number: J84.969C
• Wikidata: Q83076005
• ChEMBL ID: CHEMBL4104772
• Mol file: 5432-74-6.mol

Synonyms:2,3-dimethylquinoxaline 1,4-dioxide;2,3-DMQDO

Chemical Property of 2,3-Dimethylquinoxaline 1,4-dioxide

Chemical Property:

• Refractive Index: 1.6300 (estimate)
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• PSA: 50.92000
• Density: g/cm³
• LogP: 2.31360
• XLogP3: 0.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 0
• Exact Mass: 190.074227566
• Heavy Atom Count: 14
• Complexity: 271

Purity/Quality:

99% ^*data from raw suppliers

2,3-DIMETHYLQUINOXALINE-1,4-DIOXIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C([N+](=O)C2=CC=CC=C2N1[O-])C

Technology Process of 2,3-Dimethylquinoxaline 1,4-dioxide

There total 7 articles about 2,3-Dimethylquinoxaline 1,4-dioxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

2,3-dimethylquinoxaline (2379-55-7) → 2,3-dimethylquinoxaline-1,4-di-N-oxide (5432-74-6)

Guidance literature:

With HOF* CH₃CN; In chloroform; at 0 ℃; for 0.05h;

DOI:10.1021/jo0608016

Reference yield: 90.0%

benzofurazan oxide (480-96-6,68100-26-5) + butanone (78-93-3) → 2,3-dimethylquinoxaline-1,4-di-N-oxide (5432-74-6)

Guidance literature:

With ammonia; In methanol; at 40 - 50 ℃; for 5h;

Reference yield:

C7H6N2O + butanone (78-93-3) → 2,3-dimethylquinoxaline-1,4-di-N-oxide (5432-74-6)

Guidance literature:

With pyrrolidine; triethylamine; at 0 - 20 ℃; for 0.5h;

DOI:10.1016/j.bmcl.2017.02.049

upstream raw materials:

2,3-dimethylquinoxaline

benzofurazan oxide

butanone

2-nitro-aniline

Downstream raw materials:

2,3-dimethylquinoxaline

2,3-dimethylquinoxaline monoxide

2,11-Diphenyl-dipyrrolo[1,2-a;2',1'-c]quinoxaline-3,10-dicarboxylic acid dimethyl ester

3-methylquinoxaline-2-carboxamide