Ethyl 3-chloro-7-(trifluoromethyl)quinoxaline-2-carboxylate

Base Information

Chemical Name:Ethyl 3-chloro-7-(trifluoromethyl)quinoxaline-2-carboxylate
CAS No.:194423-79-5
Molecular Formula:C12H8ClF3N2O2
Molecular Weight:304.656
Hs Code.:
DSSTox Substance ID:DTXSID00701368
Wikidata:Q82632985
Mol file:194423-79-5.mol

Synonyms:ETHYL 3-CHLORO-7-(TRIFLUOROMETHYL)QUINOXALINE-2-CARBOXYLATE;194423-79-5;SCHEMBL2019662;DTXSID00701368;AB60396

Suppliers and Price of Ethyl 3-chloro-7-(trifluoromethyl)quinoxaline-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of Ethyl 3-chloro-7-(trifluoromethyl)quinoxaline-2-carboxylate

Chemical Property:

PSA：52.08000
LogP:3.47870
XLogP3:3.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:304.0226397
Heavy Atom Count:20
Complexity:367

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCOC(=O)C1=NC2=C(C=CC(=C2)C(F)(F)F)N=C1Cl

Technology Process of Ethyl 3-chloro-7-(trifluoromethyl)quinoxaline-2-carboxylate

There total 4 articles about Ethyl 3-chloro-7-(trifluoromethyl)quinoxaline-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 194423-79-5
ethyl 3-chloro-7-(trifluoromethyl)quinoxaline-2-carboxylate

Guidance literature:

Reference yield: 80.0%

: 143948-79-2
ethyl 3-oxo-7-(trifluoromethyl)-3,4-dihydroquinoxaline-2-carboxylate

: 194423-79-5
ethyl 3-chloro-7-(trifluoromethyl)quinoxaline-2-carboxylate

Guidance literature:: With trichlorophosphate; at 70 ℃; for 5h;

Reference yield:

: 368-71-8
4-(trifluoromethyl)-1,2-phenylenediamine

: 194423-79-5
ethyl 3-chloro-7-(trifluoromethyl)quinoxaline-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 28 percent / ethanol / 1 h / Heating

2: 80 percent / POCl₃ / 5 h / 70 °C

With trichlorophosphate; In ethanol;