1-Chloromethylbenzimidazole hydrochloride

Base Information

Chemical Name:1-Chloromethylbenzimidazole hydrochloride
CAS No.:75802-91-4
Molecular Formula:C₈H₇ClN₂*ClH
Molecular Weight:203.071
Hs Code.:
DSSTox Substance ID:DTXSID90997197

Synonyms:SCHEMBL9428892;DTXSID90997197;ZILXDWJVIMOFAJ-UHFFFAOYSA-N;1-chloromethylbenzimidazole hydrochloride;1-chloromethyl-benzimidazole hydrochloride;1-(Chloromethyl)-1H-benzimidazole--hydrogen chloride (1/1)

Suppliers and Price of 1-Chloromethylbenzimidazole hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 1-Chloromethylbenzimidazole hydrochloride

Chemical Property:

Vapor Pressure:0.000208mmHg at 25°C
Boiling Point:322.1°Cat760mmHg
Flash Point:148.6°C
Density:g/cm³
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:202.0064537
Heavy Atom Count:12
Complexity:140

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C2C(=C1)N=CN2CCl.Cl

Technology Process of 1-Chloromethylbenzimidazole hydrochloride

There total 2 articles about 1-Chloromethylbenzimidazole hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 19541-99-2
benzoimidazol-1-yl-methanol

: 75802-91-4
1-(Chloromethyl)-1H-benzimidazolium chloride

Guidance literature:: With thionyl chloride; In chloroform; for 3h; Ambient temperature;

Reference yield:

: 51-17-2,79351-71-6
benzoimidazole

: 75802-91-4
1-(Chloromethyl)-1H-benzimidazolium chloride

Guidance literature:: Multi-step reaction with 2 steps

1: 90 percent / ethanol; H₂O / 1.) reflux, 1 h, 2.) RT, 12 h

2: 99 percent / thionyl chloride / CHCl₃ / 3 h / Ambient temperature

With thionyl chloride; In ethanol; chloroform; water;

Reference yield: 58.0%

: 75802-91-4
1-(Chloromethyl)-1H-benzimidazolium chloride

: 90-05-1
2-methoxy-phenol

: 1-(2-methoxy-phenoxymethyl)-1H-benzimidazole

Guidance literature:: 2-methoxy-phenol; In N,N-dimethyl-formamide; mineral oil; for 1.33333h; Inert atmosphere; Schlenk technique;

1-(Chloromethyl)-1H-benzimidazolium chloride; In N,N-dimethyl-formamide; mineral oil; for 16h; Inert atmosphere; Schlenk technique;
DOI:10.1039/c9dt03400e