Exfoliazone

Base Information

Chemical Name:Exfoliazone
CAS No.:132627-73-7
Molecular Formula:C₁₅H₁₂N₂O₄
Molecular Weight:284.271
Hs Code.:
Mol file:132627-73-7.mol

Synonyms:3H-Phenoxazine,acetamide deriv.; Antibiotic BT 38; Exfoliazone

Suppliers and Price of Exfoliazone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of Exfoliazone

Chemical Property:

Vapor Pressure:9.63E-14mmHg at 25°C
Boiling Point:568.1°Cat760mmHg
Flash Point:297.4°C
PSA：95.92000
Density:1.45g/cm³
LogP:2.39300

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of Exfoliazone

There total 6 articles about Exfoliazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 37.0%

: 1429632-45-0
N-(3-oxo-8-[(tetrahydropyran-2-yloxy)methyl]-3H-phenoxazin-2-yl)acetamide

: 132627-73-7
Exfoliazone

Guidance literature:: With hydrogenchloride; In tetrahydrofuran; ethanol; water; at 20 ℃; for 6h; Inert atmosphere;
DOI:10.1021/jm400049z

Reference yield:

: 3011-34-5
4-hydroxy-3-nitrobenzaldehyde

: 132627-73-7
Exfoliazone

Guidance literature:: Multi-step reaction with 6 steps

1.1: sodium tetrahydroborate / methanol / 1 h / 0 °C / Inert atmosphere

2.1: pyridinium p-toluenesulfonate / dichloromethane / 16 h / 20 °C / Inert atmosphere

3.1: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C / Inert atmosphere

4.1: sodium iodate / acetone; water / 0.17 h / 20 °C / Inert atmosphere

4.2: 20 h / 20 °C / Inert atmosphere

5.1: dmap / dichloromethane / 16 h / 20 °C / Inert atmosphere

6.1: hydrogenchloride / ethanol; water; tetrahydrofuran / 6 h / 20 °C / Inert atmosphere

With hydrogenchloride; dmap; sodium tetrahydroborate; sodium iodate; palladium 10% on activated carbon; hydrogen; pyridinium p-toluenesulfonate; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; acetone;
DOI:10.1021/jm400049z

Reference yield:

: 41833-13-0
4-hydroxymethyl-2-nitrophenol

: 132627-73-7
Exfoliazone

Guidance literature:: Multi-step reaction with 5 steps

1.1: pyridinium p-toluenesulfonate / dichloromethane / 16 h / 20 °C / Inert atmosphere

2.1: palladium 10% on activated carbon; hydrogen / methanol / 2 h / 20 °C / Inert atmosphere

3.1: sodium iodate / acetone; water / 0.17 h / 20 °C / Inert atmosphere

3.2: 20 h / 20 °C / Inert atmosphere

4.1: dmap / dichloromethane / 16 h / 20 °C / Inert atmosphere

5.1: hydrogenchloride / ethanol; water; tetrahydrofuran / 6 h / 20 °C / Inert atmosphere

With hydrogenchloride; dmap; sodium iodate; palladium 10% on activated carbon; hydrogen; pyridinium p-toluenesulfonate; In tetrahydrofuran; methanol; ethanol; dichloromethane; water; acetone;
DOI:10.1021/jm400049z