6,8,11-trihydroxy-8-(1-hydroxyethyl)-10-[(4S,5S,6S)-5-hydroxy-6-methyl -4-morpholin-4-yl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5, 12-dione

Base Information

Chemical Name:6,8,11-trihydroxy-8-(1-hydroxyethyl)-10-[(4S,5S,6S)-5-hydroxy-6-methyl -4-morpholin-4-yl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5, 12-dione
CAS No.:79867-79-1
Molecular Formula:C₃₁H₃₇NO₁₁
Molecular Weight:599.635
Hs Code.:
Mol file:79867-79-1.mol

Synonyms:6,8,11-trihydroxy-8-(1-hydroxyethyl)-10-[(4S,5S,6S)-5-hydroxy-6-methyl -4-morpholin-4-yl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5, 12-dione

Suppliers and Price of 6,8,11-trihydroxy-8-(1-hydroxyethyl)-10-[(4S,5S,6S)-5-hydroxy-6-methyl -4-morpholin-4-yl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5, 12-dione

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of 6,8,11-trihydroxy-8-(1-hydroxyethyl)-10-[(4S,5S,6S)-5-hydroxy-6-methyl -4-morpholin-4-yl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5, 12-dione

Chemical Property:

Vapor Pressure:1.45E-27mmHg at 25°C
Boiling Point:807.8°C at 760 mmHg
Flash Point:442.4°C
PSA：175.45000
Density:1.51g/cm³
LogP:1.13210

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 6,8,11-trihydroxy-8-(1-hydroxyethyl)-10-[(4S,5S,6S)-5-hydroxy-6-methyl -4-morpholin-4-yl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5, 12-dione

There total 4 articles about 6,8,11-trihydroxy-8-(1-hydroxyethyl)-10-[(4S,5S,6S)-5-hydroxy-6-methyl -4-morpholin-4-yl-oxan-2-yl]oxy-1-methoxy-9,10-dihydro-7H-tetracene-5, 12-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 32.0%

: 7456-83-9
2,2'-oxybis(acetaldehyde)

: 23541-50-6
daunomycin hydrochloride

: 79867-79-1
3'-deamino-3'-morpholino-13,13-dihydrodaunorubicin

: 79867-78-0,94730-46-8
3'-deamino-3'-morpholinodaunoribicin

: 89164-75-0,89164-76-1,89617-37-8
3'-deamino-3'-(3-cyano-4-morpholinyl)-13-dihydrodaunorubicin

: 89617-36-7,89164-74-9,89196-06-5,94730-47-9
3'-deamino-3'-(3-cyano-4-morpholinyl)daunorubicin

Guidance literature:: With sodium cyanoborohydride; In water; acetonitrile;
DOI:10.1021/jm00371a014

Reference yield: 13.0%

: 7456-83-9
2,2'-oxybis(acetaldehyde)

: 23541-50-6
daunomycin hydrochloride

: 75-05-8,26809-02-9
acetonitrile

: 79867-79-1
3'-deamino-3'-morpholino-13,13-dihydrodaunorubicin

: 79867-78-0,94730-46-8
3'-deamino-3'-morpholinodaunoribicin

: 89164-75-0,89164-76-1,89617-37-8
3'-deamino-3'-(3-cyano-4-morpholinyl)-13-dihydrodaunorubicin

: 89617-36-7,89164-74-9,89196-06-5,94730-47-9
3'-deamino-3'-(3-cyano-4-morpholinyl)daunorubicin

Guidance literature:: With citrate buffer; sodium cyanoborohydride; Yield given. Multistep reaction; 1.) H₂O;
DOI:10.1021/jm00371a014

Reference yield:

: 7456-83-9
2,2'-oxybis(acetaldehyde)

: 23541-50-6
daunomycin hydrochloride

: 21794-55-8
(+)-Daunomycinone

: 79867-79-1
3'-deamino-3'-morpholino-13,13-dihydrodaunorubicin

: 79867-78-0,94730-46-8
3'-deamino-3'-morpholinodaunoribicin

Guidance literature:: With sodium cyanoborohydride; Multistep reaction. Yields of byproduct given; 1.) acetonitrile, water, RT, 45 min, 2.) 1 h;
DOI:10.1021/jm00343a004