21794-55-8

Basic information

• Product Name: DAUNOMYCINONE
• Synonyms: DAUNOMYCINONE;(8s,10s)-thoxy;5,12-naphthacenedione,8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-me;8-acetyl-7,8,9,10-tetrahydro-6,8,10,11-tetrahydroxy-1-methoxy-,(8s,10s)-12-naphthacenedione;daunomycinaglicone;daunomycinon;daunorubicinaglycone;leukaemomycinonec
• CAS NO: 21794-55-8
• Molecular Formula: C₂₁H₁₈O₈
• Molecular Weight: 398.36
• Product Categories: Various Metabolites and Impurities;Intermediates & Fine Chemicals;Metabolites;Pharmaceuticals;Metabolites & Impurities
• Mol File: 21794-55-8.mol
• Article Data: 36

Chemical Properties

• Melting Point: 208-210°C
• Boiling Point: 677.4°C at 760 mmHg
• Flash Point: 243.4°C
• Appearance: /
• Density: 1.59g/cm³
• Vapor Pressure: 2.83E-19mmHg at 25°C
• Refractive Index: 1.713
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), DMSO (Slightly), Methanol (Very Slightly, Heated)
• PKA: 7.48±0.60(Predicted)
• CAS DataBase Reference: DAUNOMYCINONE(CAS DataBase Reference)
• NIST Chemistry Reference: DAUNOMYCINONE(21794-55-8)
• EPA Substance Registry System: DAUNOMYCINONE(21794-55-8)

Safety Data

• RIDADR: UN 2811 6.1 / PGIII
• RTECS: QI9295500
• Hazardous Substances Data: 21794-55-8(Hazardous Substances Data)

Usage

Chemical Properties

Red Solid

Uses

Different sources of media describe the Uses of 21794-55-8 differently. You can refer to the following data:
1. Daunomycinone is the main metabolite of Daunorubicin (D194500).
2. A metabolite of Daunorubicin
3. The main metabolite of Daunorubicin (DNR).

InChI:InChI=1/C21H18O8/c1-8(22)21(28)6-10-13(11(23)7-21)19(26)16-15(18(10)25)17(24)9-4-3-5-12(29-2)14(9)20(16)27/h3-5,11,23,25-26,28H,6-7H2,1-2H3/t11-,21-/m0/s1

Upstream product

• 23541-50-6 daunomycin hydrochloride 
• 2161-90-2 1-methoxy-1,3-cyclohexadiene 
• 7456-83-9 2,2'-oxybis(acetaldehyde) 
• 475-38-7 5,8-Dihydroxy-1,4-naphthoquinone 
• 69986-67-0 5,8-Dihydroxy-4-trimethylsilanyloxy-3,4,4a,9a-tetrahydro-1H-anthracene-2,9,10-trione 
• 69986-68-1 4,5,8-Trihydroxy-3,4,4a,9a-tetrahydro-1H-anthracene-2,9,10-trione 
• 84201-94-5 C₂₅H₂₂O₉ 
• 84201-95-6 C₂₆H₂₄O₈ 
• 84201-96-7 (8S,10R)-8-Acetyl-6,11-diethoxy-10-hydroxy-1-methoxy-7,8,9,10-tetrahydro-naphthacene-5,12-dione 
• 74827-79-5 1,4,4a,9,9a,10-hexahydro-8-hydroxy-1-methoxy-9,10-dioxo-1,4-ethanoanthracen-5-yl(4-nitrophenyl)methyl carbonate 
• 74827-80-8 (4-nitrophenyl)methyl 1,4,9,10-tetrahydro-8-hydroxy-1-methoxy-9,10-dioxo-1,4-ethanoanthracen-5-yl carbonate 
• 88876-13-5 8-ethynyl-1,4,7,8,9,10-hexahydro-5,8,10,12-tetrahydroxy-1-methoxy-1,4-ethanonaphthacene-6,11-dione 
• 74827-83-1 1,4,6a,9,10,10a-hexahydro-5,10,12-trihydroxy-1-methoxy-1,4-ethanonaphthacene-6,8,11(7H)-trione 
• 74827-78-4 p-nitrocarbobenzoxy naphthazarin 

Downstream Products

• 72402-71-2 7-O-(2,3,6-tridesoxy-4-O-p-nitrobenzoyl-3-trifluoroacetamido-α-D-ribo-hexopyranosyl)daunomycinone 
• 120001-54-9 C₂₇H₂₁BO₈ 
• 29742-69-6 daunomycinone-14-bromide 
• 286010-11-5 C₂₆H₁₉BO₇ 
• 286010-04-6 C₂₆H₁₉BO₈ 
• 62152-30-1 (8S,10S)-1,6,8,10,11-Pentahydroxy-8-(1-hydroxy-ethyl)-7,8,9,10-tetrahydro-naphthacene-5,12-dione 
• 20982-42-7 8-Acetyl-1,6-10,11-tetrahydroxy-5,12-naphtacen-chinon 
• 20982-41-6 2-Acetyl-6,10,11-trihydroxy-1-methoxy-5,12-dioxo-5,12-dihydro-naphthacen 
• 32376-77-5 8-(1-Phenyl-ethyl)-1.6.10.11-tetrahydroxy-5.12-dihydro-naphthacen-dion-(5.12) 
• 21127-34-4 Tetracetyl-8-(α-phenylethyl)-1,6,10,11-tetrahydroxy-5,12-naphtacen-chinon 
• 871567-68-9 10-O-(4-O-acetyl-α-L-cladinosyl)daunorubicinone 
• 871567-69-0 10-O-(4-O-acetyl-α-L-oleaudropyranosyl)daunorubicinone 
• 20830-81-3 DNR 
• 24385-10-2 adriamycinone 

Relevant articles and documents

Signal transduction inhibitors, hibarimicins A, B, C, D and G produced by Microbispora. II. Structural studies

The structure of hibarimicins A, B, C, D and G which are inhibitors for tyrosine specific protein kinase are determined using spectroscopic techniques. Hibarimicins described in this report consist of a common aglycon and six deoxyhexoses. The aglycon contains a highly oxidized naphtylnaphthoquinone as a chromophore. Among them, hibarimicin B was identical with angelmicin B.

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