1,4-Difluorobutane

Base Information

• Chemical Name: 1,4-Difluorobutane
• CAS No.: 372-90-7
• Molecular Formula: C4H8F2
• Molecular Weight: 94.1043
• Hs Code.: 2903399090
• European Community (EC) Number: 671-650-6
• DSSTox Substance ID: DTXSID40190696
• Nikkaji Number: J42.715B
• Wikidata: Q18461852
• Mol file: 372-90-7.mol

Synonyms:1,4-Difluorobutane;372-90-7;BUTANE, 1,4-DIFLUORO-;BRN 1731406;3-01-00-00273 (Beilstein Handbook Reference);C4H8F2;1,4-Difluorobutan;DTXSID40190696;C4-H8-F2;MFCD01740905;AKOS006227792;LS-45693;FT-0676811

Chemical Property of 1,4-Difluorobutane

Chemical Property:

• Vapor Pressure: 96.5mmHg at 25°C
• Melting Point: 77.8 °C
• Refractive Index: 1.319
• Boiling Point: 80 °C at 760 mmHg
• PSA: 0.00000
• Density: 0.892 g/cm³
• LogP: 1.70560
• XLogP3: 1.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 94.05940658
• Heavy Atom Count: 6
• Complexity: 17.5

Purity/Quality:

98%Min ^*data from raw suppliers

1,4-Difluorobutane ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(CCF)CF

Technology Process of 1,4-Difluorobutane

There total 10 articles about 1,4-Difluorobutane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 48.0%

2,4,6,2',4',6'-hexaphenyl-1,1'-butane-1,4-diyl-bis-pyridinium; difluoride (71742-07-9) → 1,4-difluorobutane (372-90-7)

Guidance literature:

at 200 ℃; under 760 Torr;

Reference yield:

Butane-1,4-diol (110-63-4) → tetrahydrofuran (109-99-9,24979-97-3,77392-70-2) + 1,4-difluorobutane (372-90-7)

Guidance literature:

With 4,4'-diaminostilbene-2,2'-disulfonic acid; In diethylene glycol dimethyl ether; for 0.5h; Yield given. Yields of byproduct given;

Reference yield:

1,4-dichlorobutane (110-56-5) → 1,4-difluorobutane (372-90-7)

Guidance literature:

With potassium fluoride; ethylene glycol; at 170 ℃;

upstream raw materials:

1,4-dibromo-butane

1,4-dichlorobutane

tetrahydrofuran

1-fluoroethane

Refernces

• 1、 -. "HYDROFLUOROCARBON REFRIGERANT COMPOSITIONS AND USES THEREOF". . . Retrieved 2008/06/13.
• 2、 Singleton, Donald L.,Paraskevopoulos, George,Irwin, Robert S.. "Reaction of OH with CH3CH2F. The Extent of H Abstraction from the α and β Positions". . p. 2339 - 2343. Retrieved 2007/10/02.