3,6-Heptadienoic acid, 7-cyclohexyl-5-hydroxy-, tris(1-methylethyl)silyl ester, (3E,6E)-

Base Information

• Chemical Name: 3,6-Heptadienoic acid, 7-cyclohexyl-5-hydroxy-, tris(1-methylethyl)silyl ester, (3E,6E)-
• CAS No.: 194807-81-3
• Molecular Formula: C22H40O3Si
• Molecular Weight: 380.643
• Mol file: 194807-81-3.mol

Synonyms:

Chemical Property of 3,6-Heptadienoic acid, 7-cyclohexyl-5-hydroxy-, tris(1-methylethyl)silyl ester, (3E,6E)-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6-Heptadienoic acid, 7-cyclohexyl-5-hydroxy-, tris(1-methylethyl)silyl ester, (3E,6E)-

There total 1 articles about 3,6-Heptadienoic acid, 7-cyclohexyl-5-hydroxy-, tris(1-methylethyl)silyl ester, (3E,6E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

(E)-3-cyclohexylpropenal (37868-74-9) + triisopropylsilyl 3-butynoate (194807-80-2) → triisopropyl 7-cyclohexylhepta-3E,6E-dienoate (194807-81-3)

Guidance literature:

triisopropylsilyl 3-butynoate; With Schwartz's reagent; In dichloromethane; at 20 ℃; for 0.166667h;

With dimethyl zinc(II); In dichloromethane; toluene; at -78 - 0 ℃;

(E)-3-cyclohexylpropenal; In dichloromethane; toluene; at 0 - 20 ℃;

DOI:10.1021/jo990413m

Reference yield: 60.0%

triisopropyl 7-cyclohexylhepta-3E,6E-dienoate (194807-81-3) → triisopropylsilyl 7-cyclohexylhepta-2E,4E,6E-trienoate

Guidance literature:

triisopropyl 7-cyclohexylhepta-3E,6E-dienoate; With pyridine; trifluoroacetic anhydride; In tetrahydrofuran; at -10 - 5 ℃; for 1h;

With N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; at 5 - 20 ℃; for 2.5h;

DOI:10.1021/jo990413m

Reference yield:

trifluoroacetic anhydride (407-25-0) + triisopropyl 7-cyclohexylhepta-3E,6E-dienoate (194807-81-3) → C24H39F3O4Si

Guidance literature:

With pyridine; In tetrahydrofuran; at -10 - 5 ℃; for 1h;

DOI:10.1016/S0040-4039(97)01129-5

upstream raw materials:

(E)-3-cyclohexylpropenal

triisopropylsilyl 3-butynoate