1-[(4-FLUOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL

Base Information

Chemical Name:1-[(4-FLUOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL
CAS No.:195253-43-1
Molecular Formula:C16H14FNO
Molecular Weight:255.292
Hs Code.:
Mol file:195253-43-1.mol

Synonyms:[1-(4-fluorobenzyl)-1H-3-indolyl]methanol;1-(4-fluorobenzyl)-3-hydroxymethyl-1H-indole;[1-(4-Fluoro-benzyl)-1H-indol-3-yl]-methanol;

Suppliers and Price of 1-[(4-FLUOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
(1-[(4-FLUOROPHENYL)METHYL]-1H-INDOL-3-YL)METHANOL 95.00%
5MG
$ 502.55

Total 1 raw suppliers

Chemical Property of 1-[(4-FLUOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL

Chemical Property:

Melting Point:91-92 °C
Boiling Point:460.1±35.0 °C(Predicted)
PKA:14.63±0.10(Predicted)
PSA：25.16000
Density:1.18±0.1 g/cm3(Predicted)
LogP:3.32100

Purity/Quality:: (1-[(4-FLUOROPHENYL)METHYL]-1H-INDOL-3-YL)METHANOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1-[(4-FLUOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL

There total 4 articles about 1-[(4-FLUOROPHENYL)METHYL]-1H-INDOLE-3-METHANOL which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 192997-23-2
1?(4?fluorobenzyl)?1H?indole?3?carbaldehyde

: 195253-43-1
1-(3-fluorophenylmethyl)-1H-indole-3-methanol

Guidance literature:: With sodium tetrahydroborate; In methanol; Ambient temperature;
DOI:10.1002/ardp.19973300506

Reference yield:

: 487-89-8,1228547-52-1
Indole-3-carboxaldehyde

: 195253-43-1
1-(3-fluorophenylmethyl)-1H-indole-3-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / NaH / dimethylsulfoxide / 2 h / 20 °C

2: 80 percent / LiAlH₄ / tetrahydrofuran / 0.5 h / 20 °C

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1016/S0223-5234(02)00005-3

Reference yield:

: 352-11-4
1-chloromethyl-4-fluorobenzene

: 195253-43-1
1-(3-fluorophenylmethyl)-1H-indole-3-methanol

Guidance literature:: Multi-step reaction with 2 steps

1: 76 percent / NaH / dimethylsulfoxide / 2 h / 20 °C

2: 80 percent / LiAlH₄ / tetrahydrofuran / 0.5 h / 20 °C

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; dimethyl sulfoxide;
DOI:10.1016/S0223-5234(02)00005-3