1(2H)-Pyridinecarboxylic acid, 2-(3-butenyl)-3,4-dihydro-4-oxo-5-[tris(1-methylethyl)silyl]-, (1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl ester, (2S)-

Base Information

Chemical Name:1(2H)-Pyridinecarboxylic acid, 2-(3-butenyl)-3,4-dihydro-4-oxo-5-[tris(1-methylethyl)silyl]-, (1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl ester, (2S)-
CAS No.:197841-58-0
Molecular Formula:C₃₄H₅₃NO₃Si
Molecular Weight:551.885
Hs Code.:

1(2H)-Pyridinecarboxylic acid,
2-(3-butenyl)-3,4-dihydro-4-oxo-5-[tris(1-methylethyl)silyl]-,
(1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl ester, (2S)-

Synonyms:

Suppliers and Price of 1(2H)-Pyridinecarboxylic acid, 2-(3-butenyl)-3,4-dihydro-4-oxo-5-[tris(1-methylethyl)silyl]-, (1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl ester, (2S)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 3 raw suppliers

Chemical Property of 1(2H)-Pyridinecarboxylic acid, 2-(3-butenyl)-3,4-dihydro-4-oxo-5-[tris(1-methylethyl)silyl]-, (1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl ester, (2S)-

Chemical Property:

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 1(2H)-Pyridinecarboxylic acid, 2-(3-butenyl)-3,4-dihydro-4-oxo-5-[tris(1-methylethyl)silyl]-, (1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl ester, (2S)-

There total 3 articles about 1(2H)-Pyridinecarboxylic acid, 2-(3-butenyl)-3,4-dihydro-4-oxo-5-[tris(1-methylethyl)silyl]-, (1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl ester, (2S)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 126378-42-5
4-methoxy-3-(trisopropylsilyl)pyridine

: 197841-58-0
(S)-2-But-3-enyl-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1S,2R)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 1.5 h / -42 °C

2: 2.) oxalic acid / 1.) THF, -78 deg C, 4 h, 2.) H₂O, room temperature, overnight

With oxalic acid; In toluene;
DOI:10.1021/jo971448u

Reference yield:

: 161693-64-7
(1S,2R)-2-(1-methyl-1-phenylethyl)cyclohexyl chloroformate

: 197841-58-0
(S)-2-But-3-enyl-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1S,2R)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 1.5 h / -42 °C

2: 2.) oxalic acid / 1.) THF, -78 deg C, 4 h, 2.) H₂O, room temperature, overnight

With oxalic acid; In toluene;
DOI:10.1021/jo971448u

Reference yield:

: 7103-09-5
4-but-1-enylmagnesium bromide

: 4-Methoxy-1-[(1S,2R)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-3-triisopropylsilanyl-pyridinium; chloride

: 197841-58-0
(S)-2-But-3-enyl-4-oxo-5-triisopropylsilanyl-3,4-dihydro-2H-pyridine-1-carboxylic acid (1S,2R)-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester

Guidance literature:: With oxalic acid; Yield given. Multistep reaction; 1.) THF, -78 deg C, 4 h, 2.) H₂O, room temperature, overnight;
DOI:10.1021/jo971448u