Benzenamine, N-(2-chloro-2,2-difluoroethylidene)-4-methoxy-

Base Information

Chemical Name:Benzenamine, N-(2-chloro-2,2-difluoroethylidene)-4-methoxy-
CAS No.:198273-38-0
Molecular Formula:C9H8ClF2NO
Molecular Weight:219.618
Hs Code.:
DSSTox Substance ID:DTXSID00442103
Nikkaji Number:J928.162B,J2.498.505I

Synonyms:198273-38-0;Benzenamine, N-(2-chloro-2,2-difluoroethylidene)-4-methoxy-;DTXSID00442103;4-Methoxy-N-(2,2-difluoro-2-chloroethylidene)aniline;N-[(E)-2-Chloro-2,2-difluoroethylidene]-4-methoxyaniline

Suppliers and Price of Benzenamine, N-(2-chloro-2,2-difluoroethylidene)-4-methoxy-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of Benzenamine, N-(2-chloro-2,2-difluoroethylidene)-4-methoxy-

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:219.0262479
Heavy Atom Count:14
Complexity:203

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N=CC(F)(F)Cl

Technology Process of Benzenamine, N-(2-chloro-2,2-difluoroethylidene)-4-methoxy-

There total 1 articles about Benzenamine, N-(2-chloro-2,2-difluoroethylidene)-4-methoxy- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 104-94-9
4-methoxy-aniline

: 103813-74-7
chlorodifluoroacetaldehyde ethyl hemiacetal

: 198273-38-0
C₉H₈ClF₂NO

Guidance literature:: In toluene; for 1.5h; Reflux; Inert atmosphere; Dean-Stark;
DOI:10.1021/acs.joc.8b01743

Reference yield: 99.0%

: 61550-02-5
(furan-2-yloxy)-trimethylsilane

: 198273-38-0
C₉H₈ClF₂NO

: trans-5-(2-chloro-2,2-difluoro-1-(4-methoxyphenylamino)ethyl)furan-2(5H)-one

Guidance literature:: (furan-2-yloxy)-trimethylsilane; C₉H₈ClF₂NO; With ethanol; (S)-4-tert-butyl-2-((S)-2'-(diphenylphosphino)-1,1'-binaphthyl-2-yl)-4,5-dihydrooxazole; silver(I) acetate; In tetrahydrofuran; at -78 ℃; Molecular sieve;

With acetic acid; In tetrahydrofuran; methanol; ethanol; at -78 - 22 ℃; optical yield given as %ee; enantioselective reaction;
DOI:10.1016/j.tetasy.2010.05.025

Reference yield: 76.0%

: 198273-38-0
C₉H₈ClF₂NO

: 76862-09-4
methyl N-(4-chlorobenzylidene)glycinate

: 1446437-11-1
(2R,4R,5R)-methyl 5-(chlorodifluoromethyl)-2-(4-chlorophenyl)-1-(4-methoxyphenyl)-5-(trifluoromethyl)imidazoline-4-carboxylate

Guidance literature:: With tetrakis(acetonitrile)copper(I)tetrafluoroborate; C₂₅H₂₅FeOP; triethylamine; In diethyl ether; at -20 ℃; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c3cc43025a DOI:10.1039/c3cc43025a