1-Azido-2-(phenylethynyl)benzene

Base Information

Chemical Name:1-Azido-2-(phenylethynyl)benzene
CAS No.:199277-23-1
Molecular Formula:C14H9N3
Molecular Weight:219.246
Hs Code.:
DSSTox Substance ID:DTXSID90571158
Nikkaji Number:J916.726I
Wikidata:Q82458783

Synonyms:1-Azido-2-(phenylethynyl)benzene;199277-23-1;DTXSID90571158

Suppliers and Price of 1-Azido-2-(phenylethynyl)benzene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1-Azido-2-(phenylethynyl)benzene

Chemical Property:

XLogP3:4.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:219.079647300
Heavy Atom Count:17
Complexity:350

Purity/Quality:: 99%, ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C#CC2=CC=CC=C2N=[N+]=[N-]

Technology Process of 1-Azido-2-(phenylethynyl)benzene

There total 4 articles about 1-Azido-2-(phenylethynyl)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 54467-95-7
1-azido-2-iodo-benzene

: 536-74-3
phenylacetylene

: 199277-23-1
1-azido-2-(phenylethynyl)benzene

Guidance literature:: With copper(l) iodide; triethylamine; bis-triphenylphosphine-palladium(II) chloride; In dichloromethane; at 20 ℃; for 1h;
DOI:10.3987/COM-03-9726

Reference yield: 93.0%

: 13141-38-3
2-phenylethynylaniline

: 199277-23-1
1-azido-2-(phenylethynyl)benzene

Guidance literature:: 2-phenylethynylaniline; With sulfuric acid; sodium nitrite; In water; N,N-dimethyl-formamide; acetonitrile; at 0 ℃; for 0.5h;

With sodium azide; In water; N,N-dimethyl-formamide; acetonitrile; at 0 - 20 ℃; for 2h;
DOI:10.1016/j.jfluchem.2021.109878

Reference yield:

: 615-43-0
2-iodophenylamine

: 199277-23-1
1-azido-2-(phenylethynyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: Pd(PPh₃)4, piperidine / 6 h / Ambient temperature

2: 1) NaNO₂, HCl, 2) NaN₃ / y / 2) H₂O, 40 min, RT

With piperidine; hydrogenchloride; tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium azide; sodium nitrite; y;
DOI:10.1002/(SICI)1099-0690(199806)1998:6<1219::AID-EJOC1219>3.0.CO;2-V