Silane, dimethyl(3-methyl-1-oxobutyl)phenyl-

Base Information

• Chemical Name: Silane, dimethyl(3-methyl-1-oxobutyl)phenyl-
• CAS No.: 199847-86-4
• Molecular Formula: C13H20OSi
• Molecular Weight: 220.387
• DSSTox Substance ID: DTXSID80479295
• Nikkaji Number: J2.158.017A
• Wikidata: Q82313283
• Mol file: 199847-86-4.mol

Synonyms:Silane, dimethyl(3-methyl-1-oxobutyl)phenyl-;199847-86-4;DTXSID80479295

Chemical Property of Silane, dimethyl(3-methyl-1-oxobutyl)phenyl-

Chemical Property:

• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 220.128341792
• Heavy Atom Count: 15
• Complexity: 215

Purity/Quality:

99%, ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CC(=O)[Si](C)(C)C1=CC=CC=C1

Technology Process of Silane, dimethyl(3-methyl-1-oxobutyl)phenyl-

There total 5 articles about Silane, dimethyl(3-methyl-1-oxobutyl)phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

3-bromo-2,2-dimethyl-1-(dimethylphenylsilyl)propan-1-one (266329-24-2) → 1-(dimethylphenylsilyl)-3-methylbutan-1-one (199847-86-4)

Guidance literature:

With 2,2'-azobis(isobutyronitrile); tri-n-butyl-tin hydride; In benzene;

DOI:10.1021/jo9912855

Reference yield: 30.0%

(2-isobutyl-[3]dithian-2-yl)-dimethylphenylsilane → 1-(dimethylphenylsilyl)-3-methylbutan-1-one (199847-86-4)

Guidance literature:

With chloroamine-T; In methanol; water; at 0 - 20 ℃;

DOI:10.1016/j.tet.2004.10.099

Reference yield:

2,2-dimethyl-1-(dimethylphenylsilyl)-3-(tetrahydropyran-2-yloxy)propan-1-one (266329-37-7) → 1-(dimethylphenylsilyl)-3-methylbutan-1-one (199847-86-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 41 percent / CBr₄; PPh₃ / CH₂Cl₂ / 0 - 20 °C

2: 62 percent / n-Bu₃SnH; AIBN / benzene

With 2,2'-azobis(isobutyronitrile); carbon tetrabromide; tri-n-butyl-tin hydride; triphenylphosphine; In dichloromethane; benzene; 1: Bromination / 2: Reduction;

DOI:10.1021/jo9912855

upstream raw materials:

3-bromo-2,2-dimethyl-1-(dimethylphenylsilyl)propan-1-one

2-(2-methylpropyl)-1,3-dithiane

2,2-dimethyl-1-(dimethylphenylsilyl)-3-(tetrahydropyran-2-yloxy)propan-1-one

2,2-dimethyl-1-(dimethylphenylsilyl)-3-(tetrahydropyran-2-yloxy)propan-1-ol

Downstream raw materials:

3-[(Z)-1-(Dimethyl-phenyl-silanyl)-3-methyl-but-1-enylsulfanyl]-propionic acid ethyl ester

3-[(Z)-1-(Dimethyl-phenyl-silanyl)-3-methyl-but-1-enylsulfanyl]-propionic acid methyl ester

(Z)-1-[dimethyl(phenyl)silyl]-3-methylbut-1-enethiol