cis-Boc-4-methoxy-D-proline

Base Information

Chemical Name:cis-Boc-4-methoxy-D-proline
CAS No.:200184-87-8
Molecular Formula:C11H19NO5
Molecular Weight:245.276
Hs Code.:
European Community (EC) Number:695-651-6
DSSTox Substance ID:DTXSID30466579
Wikidata:Q76421538
Mol file:200184-87-8.mol

Synonyms:200184-87-8;CIS-BOC-4-METHOXY-D-PROLINE;(2r,4r)-1-(tert-butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid;cis-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid;(2R,4R)-4-methoxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic Acid;(2R,4R)-1-[(tert-butoxy)carbonyl]-4-methoxypyrrolidine-2-carboxylic acid;SCHEMBL92869;DTXSID30466579;COHIMMPWCAHSFN-HTQZYQBOSA-N;MFCD22418970;(2R,4R)-N-Boc-4-MeO-Pro-OH;AKOS030612389;AS-41209;CS-0435059;EN300-158250;(4R)-1-(tert-butoxycarbonyl)-4-methoxy-D-proline;cis-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid;(2R,4R)-1-(t-Butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid;(2R,4R)-1-(tert-Butoxycarbonyl)-4-methoxypyrrolidine-2- carboxylic acid;(2R,4R)-4-Methoxy-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester;(2R, 4R)-4-methoxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid

Suppliers and Price of cis-Boc-4-methoxy-D-proline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
Cis-1-(tert-butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid
1g
$ 677.00

Alichem
Cis-1-(tert-butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid
250mg
$ 298.10

Total 7 raw suppliers

Chemical Property of cis-Boc-4-methoxy-D-proline

Chemical Property:

PSA：76.07000
LogP:1.03330
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:4
Exact Mass:245.12632271
Heavy Atom Count:17
Complexity:310

Purity/Quality:

97% ^*data from raw suppliers

Cis-1-(tert-butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylicacid ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CC(CC1C(=O)O)OC
Isomeric SMILES:CC(C)(C)OC(=O)N1C[C@@H](C[C@@H]1C(=O)O)OC

Technology Process of cis-Boc-4-methoxy-D-proline

There total 4 articles about cis-Boc-4-methoxy-D-proline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 135042-12-5,946610-68-0
(4R)-1-(tert-butoxycarbonyl)-4-hydroxy-D-proline

: 74-88-4
methyl iodide

: 200184-87-8
(2R,4R)-1-(tert-butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid

Guidance literature:: With sodium hydride; In tetrahydrofuran; at 0 - 5 ℃;

Reference yield: 91.0%

: 200184-87-8
(2R,4R)-1-(tert-butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid

Guidance literature:: With sodium hydride; In tetrahydrofuran; mineral oil; at -10 ℃; for 0.5h;

In tetrahydrofuran; mineral oil; at -10 - 20 ℃; for 16h;

Reference yield: 88.0%

: 200184-86-7
(2R,4R)-1-tert-butyl 2-methyl 4-methoxypyrrolidine-1,2-dicarboxylate

: 200184-87-8
(2R,4R)-1-(tert-butoxycarbonyl)-4-methoxypyrrolidine-2-carboxylic acid

Guidance literature:: O₁-tert-butyl O₂-methyl (2R,4R)-4-methoxypyrrolidine-1,2-dicarboxylate; With lithium hydroxide; In tetrahydrofuran; water; at 20 ℃; for 5h;

With hydrogenchloride; In tetrahydrofuran; 1,4-dioxane; water;