4-Cyclopentylaniline

Base Information

• Chemical Name: 4-Cyclopentylaniline
• CAS No.: 20029-53-2
• Molecular Formula: C11H15N
• Molecular Weight: 161.247
• Hs Code.: 2921499090
• European Community (EC) Number: 831-780-8
• DSSTox Substance ID: DTXSID70473444
• Nikkaji Number: J506.378G
• Mol file: 20029-53-2.mol

Synonyms:4-cyclopentylaniline;20029-53-2;4-CYCLOPENTYLBENZENAMINE;BENZENAMINE,4-CYCLOPENTYL-;Benzenamine, 4-cyclopentyl-;SCHEMBL1064153;DTXSID70473444;BKMMERYBDMQMFJ-UHFFFAOYSA-N;MFCD11111746;AKOS006308210;AS-30637;CS-0210599;EN300-200096

Chemical Property of 4-Cyclopentylaniline

Chemical Property:

• PSA: 26.02000
• LogP: 3.50760
• XLogP3: 3.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 1
• Exact Mass: 161.120449483
• Heavy Atom Count: 12
• Complexity: 130

Purity/Quality:

≥95% ^*data from raw suppliers

4-cyclopentylbenzenamine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1CCC(C1)C2=CC=C(C=C2)N

Technology Process of 4-Cyclopentylaniline

There total 16 articles about 4-Cyclopentylaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-(2-cyclopenten-1-yl)aniline (118560-25-1) → (4-aminophenyl)cyclopentane (20029-53-2)

Guidance literature:

With hydrogen; nickel; In ethanol; for 3h;

DOI:10.1007/bf02499087

Reference yield: 94.0%

1-(4-nitrophenyl)cyclopentene (38805-71-9) → (4-aminophenyl)cyclopentane (20029-53-2)

Guidance literature:

With hydrogen; palladium 10% on activated carbon; In methanol; dichloromethane; at 20 ℃; for 1h;

Reference yield: 91.0%

4-(cyclopentyl)-nitrobenzene (89410-18-4) → (4-aminophenyl)cyclopentane (20029-53-2)

Guidance literature:

With hydrogen; palladium on activated charcoal; In ethanol;

DOI:10.1016/0223-5234(92)90188-7

upstream raw materials:

N-(4-Cyclopentylphenyl)acetamide

4-(cyclopentyl)-nitrobenzene

4-Cyclopentylacetophenone Oxime

4-(2-cyclopenten-1-yl)aniline

Downstream raw materials:

1-(4-cyclopentyl-phenyl)-2,5-dimethyl-pyrrole

2-bromo-4-cyclopentylaniline

4,5,6,7-tetrachloro-2-(4-cyclopentyl-phenyl)-isoindoline-1,3-dione

4-(4-(4-cyclopentylphenyl)-1-piperazinyl)-1-(4-fluorophenyl)butan-1-one

Refernces

• 1、 Fortin, Jessica S.,Cote, Marie-France,Lacroix, Jacques,Desjardins, Michel,Petitclerc, Eric,C.-Gaudreault, Rene. "Selective alkylation of βII-tubulin and thioredoxin-1 by structurally related subsets of aryl chloroethylureas leading to either anti-microtubules or redox modulating agents". . p. 7277 - 7290. Retrieved 2008/12/22.
• 2、 -. "Methods and compositions for treating pain". Page/Page column 52. . Retrieved 2010/11/28.