2-(2,6-Dichlorophenoxy)Acetyl Chloride

Base Information

• Chemical Name: 2-(2,6-Dichlorophenoxy)Acetyl Chloride
• CAS No.: 20143-46-8
• Molecular Formula: C8H5Cl3O2
• Molecular Weight: 239.48300
• DSSTox Substance ID: DTXSID50549494
• Wikidata: Q82428549
• Mol file: 20143-46-8.mol

Synonyms:20143-46-8;2-(2,6-Dichlorophenoxy)Acetyl Chloride;SCHEMBL9505425;DTXSID50549494;(2,6-Dichlorophenoxy)acetyl chloride;G68529

Chemical Property of 2-(2,6-Dichlorophenoxy)Acetyl Chloride

Chemical Property:

• PSA: 26.30000
• LogP: 3.13760
• XLogP3: 3.7
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 237.935512
• Heavy Atom Count: 13
• Complexity: 176

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC(=C(C(=C1)Cl)OCC(=O)Cl)Cl

Technology Process of 2-(2,6-Dichlorophenoxy)Acetyl Chloride

There total 2 articles about 2-(2,6-Dichlorophenoxy)Acetyl Chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,6-dichlorophenoxyacetic acid (575-90-6) → (2,6-dichlorophenoxy)-acetyl chloride (20143-46-8)

Guidance literature:

With thionyl chloride;

Reference yield:

2,6-Dichlorophenol (87-65-0) → (2,6-dichlorophenoxy)-acetyl chloride (20143-46-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide

2: thionyl chloride

With thionyl chloride; sodium hydroxide;

DOI:10.1021/jf104247w

Reference yield: 75.0%

(2,6-dichlorophenoxy)-acetyl chloride (20143-46-8) + dimethyl 1-hydroxy-1-(3-nitrophenyl)methylphosphonate (103796-61-8) → O,O-dimethyl α-(2,6-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate (904702-60-9)

Guidance literature:

With pyridine; In chloroform; at 10 - 42 ℃;

DOI:10.1021/jf104247w

upstream raw materials:

2,6-dichlorophenoxyacetic acid

2,6-Dichlorophenol

Downstream raw materials:

1-(5-Amino-3-methylsulfanyl-[1,2,4]triazol-1-yl)-2-(2,6-dichloro-phenoxy)-ethanone

2-(2,6-Dichloro-phenoxy)-N-(5-methylsulfanyl-2H-[1,2,4]triazol-3-yl)-acetamide

C₁₆H₁₆Cl₂NO₅P

O,O-dimethyl α-(2,6-dichlorophenoxyacetoxy)-3-nitrobenzylphosphonate