Cyclopropanecarbothioamide

Base Information

• Chemical Name: Cyclopropanecarbothioamide
• CAS No.: 20295-34-5
• Molecular Formula: C4H7NS
• Molecular Weight: 101.172
• Hs Code.: 2930909090
• Mol file: 20295-34-5.mol

Synonyms:CYCLOPROPANETHIOCARBOXAMIDE;CYCLOPROPANECARBOTHIOIC ACID AMIDE;cyclopropyl thioamide;;cyclopropylthioacetamide;;cyclopropane carbothioamide;;aminocyclopropylmethane-1-thione;;

Chemical Property of Cyclopropanecarbothioamide

Chemical Property:

• Vapor Pressure: 1.066mmHg at 25°C
• Melting Point: 111-113℃
• Refractive Index: 1.656
• Boiling Point: 176.9±23.0 oC (760 Torr), Calc.*
• PKA: 13.19±0.20(Predicted)
• Flash Point: 60.8±22.6 oC, Calc.*
• PSA: 58.11000
• Density: 1.272±0.06 g/cm3 (20 oC 760 Torr), Calc
• LogP: 1.38280

Purity/Quality:

99%, ^*data from raw suppliers

Cyclopropanecarbothioamide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Description: Cyclopropanecarbothioamide is used for purification of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas during the simple-step reaction. It is also a useful chemical during the proteomics study. Recent study has also used it for synthesis of a novel heterocyclic compound, CE-125, which can improve working memory in the radial arm maze and modulate the dopamine receptor D1R in frontal cortex of the Sprague-Dawley rat.
• Uses: Cyclopropanecarbothioamide is used for purification in single-step preparation of thiazolo [5, 4-b] pyridine-and thiazolo [5, 4-c] pyridine derivatives from chloronitropyridines and thioamides, or thioureas.

Technology Process of Cyclopropanecarbothioamide

There total 3 articles about Cyclopropanecarbothioamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

Cyclopropancarbamid (6228-73-5) → cyclopropanecarbothioamide (20295-34-5)

Guidance literature:

With Lawessons reagent; sodium carbonate; In tetrahydrofuran; at 80 ℃; for 2h;

Reference yield: 97.0%

cyclopropropanecarbonitrile (5500-21-0) → cyclopropanecarbothioamide (20295-34-5)

Guidance literature:

With sodium hydrogensulfide; diethyl amine hydrochloride; In 1,4-dioxane; water; at 55 ℃; for 42h;

DOI:10.1080/00397910500377099

Reference yield:

→ cyclopropanecarbothioamide (20295-34-5)

Guidance literature:

Cyclopropancarbonitril, H2S;

DOI:10.1021/je60036a040

upstream raw materials:

cyclopropropanecarbonitrile

Cyclopropancarbamid

Downstream raw materials:

methyl 2-cyclopropyl-5-phenyl-1,3-thiazole-4-carboxylate

2-cyclopropylthiazole-5-carbaldehyde

4-(chloromethyl)-2-cyclopropylthiazole

2-cyclopropyl-5-(3-methyl-phenyl)-thiazole-4-carboxylic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 20295-34-5 Cyclopropanecarbothioamide

Send

Send

Metric Ton KG G Pound L ML

Send

Send