1-Bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene

Base Information

• Chemical Name: 1-Bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene
• CAS No.: 204503-25-3
• Molecular Formula: C11H13BrO
• Molecular Weight: 241.128
• DSSTox Substance ID: DTXSID80578792
• Nikkaji Number: J966.861F
• Mol file: 204503-25-3.mol

Synonyms:204503-25-3;1-Bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene;1-bromo-4-(3-methylbut-2-enoxy)benzene;1-Bromo-4-[(3-methylbut-2-en-1-yl)oxy]benzene;SCHEMBL670129;Benzene, 1-bromo-4-[(3-methyl-2-buten-1-yl)oxy]-;DTXSID80578792;MFCD11127734;AKOS000202936;AS-47318;F13242

Chemical Property of 1-Bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene

Chemical Property:

• Boiling Point: 289.9±15.0 °C(Predicted)
• PSA: 9.23000
• Density: 1.275±0.06 g/cm3(Predicted)
• LogP: 3.79410
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 240.01498
• Heavy Atom Count: 13
• Complexity: 165

Purity/Quality:

99% ^*data from raw suppliers

1-Bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(=CCOC1=CC=C(C=C1)Br)C

Technology Process of 1-Bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene

There total 4 articles about 1-Bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

4-bromo-phenol (106-41-2) + prenyl bromide (870-63-3) → 1-bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene (204503-25-3)

Guidance literature:

With potassium carbonate; potassium iodide; In acetone; at 80 ℃; for 12h;

DOI:10.1016/j.tet.2008.02.077

Reference yield: 81.0%

4-bromo-phenol (106-41-2) + 3-methyl-2-buten-1-ol (556-82-1) → 1-bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene (204503-25-3)

Guidance literature:

With di-isopropyl azodicarboxylate; triphenylphosphine; In tetrahydrofuran; for 1.5h; Reflux;

DOI:10.1021/acs.orglett.0c01395

Reference yield: 16.0%

4-bromo-phenol (106-41-2) + prenyl bromide (870-63-3) → 1-bromo-4-((3-methylbut-2-en-1-yl)oxy)benzene (204503-25-3) + 4-bromo-2,6-bis(3-methyl-2-butenyl)-phenol (364358-96-3) + 4-bromo-2,6-di(3-methyl-2-butenyl)phenyl (3-methyl-2-butenyl) ether

Guidance literature:

With 10percent NaOH; at 20 ℃; for 5h;

DOI:10.1021/jo0056904

upstream raw materials:

4-bromo-phenol

prenyl bromide

2-methyl-3-buten-2-ol

3-methyl-2-buten-1-ol

Downstream raw materials:

(4-[(3-METHYLBUT-2-EN-1-YL)OXY]PHENYL)BORANEDIOL

3,4-dihydro-2,2-dimethyl-2H-1-benzopyran-6-carboxaldehyde

himanimide B

3-benzyl-4-[4-(3-methylbut-2-enoxy)phenyl]-1H-pyrrole-2,5-dione