4-Phenyl-1-piperidin-4-yl-1,3-dihydro-2H-imidazol-2-one

Base Information

• Chemical Name: 4-Phenyl-1-piperidin-4-yl-1,3-dihydro-2H-imidazol-2-one
• CAS No.: 205058-28-2
• Molecular Formula: C14H17N3O
• Molecular Weight: 243.308
• Hs Code.: 2933990090
• European Community (EC) Number: 681-550-4
• DSSTox Substance ID: DTXSID40463059
• Wikidata: Q82287793
• Mol file: 205058-28-2.mol

Synonyms:205058-28-2;4-Phenyl-1-piperidin-4-yl-1,3-dihydro-2H-imidazol-2-one;4-phenyl-1-(piperidin-4-yl)-1H-imidazol-2(3H)-one;4-Phenyl-1-(4-piperidinyl)-4-imidazolin-2-one;5-phenyl-3-piperidin-4-yl-1H-imidazol-2-one;MFCD08061015;2H-Imidazol-2-one, 1,3-dihydro-4-phenyl-1-(4-piperidinyl)-;4-phenyl-1-(piperidin-4-yl)-2,3-dihydro-1H-imidazol-2-one;SCHEMBL2102005;SCHEMBL4735509;DTXSID40463059;OPCVKWIYGHICKG-UHFFFAOYSA-N;AKOS005255483;MS-22694;CS-0318323;FT-0678617;4-Phenyl-1-(piperidin-4-yl)-1H-imidazol-2-ol;A924548;4-phenyl-(piperidin-4-yl)-1H-imidazol-2(3H)-one;W-206525;1,3-dihydro-1-(4-piperidinyl)-4-phenyl-2(2H)-imidazolone;4-Phenyl-1-(piperidin-4-yl)-1,3-dihydro-2H-imidazol-2-one

Chemical Property of 4-Phenyl-1-piperidin-4-yl-1,3-dihydro-2H-imidazol-2-one

Chemical Property:

• Melting Point: 235oC
• PSA: 49.82000
• Density: 1.193g/cm3
• LogP: 2.09670
• XLogP3: 1.1
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 243.137162174
• Heavy Atom Count: 18
• Complexity: 341

Purity/Quality:

97% ^*data from raw suppliers

4-Phenyl-1-piperidin-4-yl-1,3-dihydro-2H-imidazol-2-one 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

Useful:

• Canonical SMILES: C1CNCCC1N2C=C(NC2=O)C3=CC=CC=C3

Technology Process of 4-Phenyl-1-piperidin-4-yl-1,3-dihydro-2H-imidazol-2-one

There total 3 articles about 4-Phenyl-1-piperidin-4-yl-1,3-dihydro-2H-imidazol-2-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-(1,3-dihydro-2(2H)-oxo-4-phenyl-imidazol-1-yl)-1-(1,1-dimethylethoxycarbonyl)piperidine (205058-11-3) → 4-(1,3-dihydro-4-phenyl-2(2H)-oxoimidazol-1-yl)piperidine (205058-28-2)

Guidance literature:

Reference yield:

4-[1,3-dihydro-4-(4-methoxyphenyl)-2(2H)-oxoimidazol-1-yl]-1-(1,1-dimethylethoxycarbonyl)-piperidine → 4-(1,3-dihydro-4-phenyl-2(2H)-oxoimidazol-1-yl)piperidine (205058-28-2)

Guidance literature:

Reference yield:

→ 4-(1,3-dihydro-4-phenyl-2(2H)-oxoimidazol-1-yl)piperidine (205058-28-2)

Guidance literature:

With trifluoroacetic acid; In dichloromethane; at 0 - 20 ℃; for 20h;

upstream raw materials:

4-(1,3-dihydro-2(2H)-oxo-4-phenyl-imidazol-1-yl)-1-(1,1-dimethylethoxycarbonyl)piperidine

Downstream raw materials:

C₂₉H₃₆N₄O₂

C₂₈H₃₁N₅O₄

C₃₇H₄₇N₇O₃

C₂₇H₂₉N₅O₄