POLY(DL-LACTIDE)

Base Information

• Chemical Name: POLY(DL-LACTIDE)
• CAS No.: 34346-01-5
• Molecular Formula: >(C3H6O3)n^.(C2H4O3)n
• Molecular Weight: 166.13
• Mol file: 34346-01-5.mol

Synonyms:Resolut ST;Resomer RG 858;Resomer RG 502;Propanoic acid,2-hydroxy-,polymers,polymer with hydroxyacetic acid;Resomer RG 502H;Resomer RG 504H;

Chemical Property of POLY(DL-LACTIDE)

Chemical Property:

• Vapor Pressure: 0.015mmHg at 25°C
• Melting Point: 262 °C(lit.)
• Boiling Point: 227.6°C at 760 mmHg
• Flash Point: 109.9°C
• Density: 1.53 g/mL at 25 °C(lit.)
• Storage Temp.: 2-8°C

Purity/Quality:

99% ^*data from raw suppliers

Poly(D,L-lactide) inherent viscosity 0.55-0.75?dL/g?(lit.) ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Description: Poly(D-lactide) (PDLA), a polymer of a stereospecific cyclic di-ester of lactic acid, is used in biomaterial research for the development of devices such as therapeutic drug delivery vessels. Poly(D-lactide) is used for the preparation of microparticles and resorbable polylactide scaffolds. By poly (D-lactide） made products biological compatibility is good, after the in vivo degradation product by the metabolism out of the body, no harmful and toxic side effects on the human body.
• Uses: Poly D-lactide is a bioabsorbable and degradable material. Poly D-lactide can be used in medical fields, such as disposable infusion devices, non-removable surgical sutures; controlled release and slow release packaging agents; tissue engineering scaffolds, bone fixation and bone repair materials, microcapsules for injection, microspheres, implant And animal organs support elastomers and other materials. At present, it is widely used in the fields of medicine, such as disposable infusion apparatus, free disassembly type suture; drug controlled release, sustained release agent packaging; scaffolds for tissue engineering, bone fixation and bone repairing material, injection with of microcapsules and microspheres, implants and animal organs elastomer material support. Surgical aid (surgical suture material, absorbable). Used in Drug Delivery including coating nanoparticles. Can be end-group functionalizated or used as a macroinitiator/block precursor.

Technology Process of POLY(DL-LACTIDE)

There total 2 articles about POLY(DL-LACTIDE) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

glycolic Acid (79-14-1) + aqueous lactic acid → glycolic acid-lactic acid (34346-01-5)

Guidance literature:

Reference yield:

→ glycolic acid-lactic acid (34346-01-5)

Guidance literature:

upstream raw materials:

glycolic Acid

Refernces

• 1、 -. "Sustained-release preparation". . . Retrieved 2008/06/13.
• 2、 -. "Method of producing sustained-release microcapsules". . . Retrieved 2008/06/13.