2,4(1H,3H)-Pyrimidinedione, 6-amino-5-hydroxy- (9CI)

Base Information

• Chemical Name: 2,4(1H,3H)-Pyrimidinedione, 6-amino-5-hydroxy- (9CI)
• CAS No.: 3914-34-9
• Molecular Formula: C4H5N3O3
• Molecular Weight: 143.102
• Mol file: 3914-34-9.mol

Synonyms:

Chemical Property of 2,4(1H,3H)-Pyrimidinedione, 6-amino-5-hydroxy- (9CI)

Chemical Property:

• Vapor Pressure: 1.47E-14mmHg at 25°C
• Melting Point: > 200°C (dec)
• Boiling Point: 590.9°Cat760mmHg
• Flash Point: 311.2°C
• Density: 1.676g/cm³
• Storage Temp.: -20°C Freezer, Under inert atmosphere
• Solubility.: DMSO (Slightly), Water (Slightly)

Purity/Quality:

98%+ ^*data from raw suppliers

Isouramil ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Isouramil is an aglycon of vicine and convicine, and a causative agent of favism.

Technology Process of 2,4(1H,3H)-Pyrimidinedione, 6-amino-5-hydroxy- (9CI)

There total 3 articles about 2,4(1H,3H)-Pyrimidinedione, 6-amino-5-hydroxy- (9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ 6-amino-5-hydroxy-1H-pyrimidine-2,4-dione (3914-34-9)

Guidance literature:

With diammonium sulfide;

DOI:10.1073/pnas.18.7.490

Reference yield:

6-amino-5-tetrahydropyran-2-yloxy-1H-pyrimidine-2,4-dione (98961-44-5) → 6-amino-5-hydroxy-1H-pyrimidine-2,4-dione (3914-34-9)

Guidance literature:

With sulfuric acid;

DOI:10.1039/jr9560002124

Reference yield:

→ 6-amino-5-hydroxy-1H-pyrimidine-2,4-dione (3914-34-9)

Guidance literature:

5-Hydroxy-6-nitroso-uracil-dihydrat, Red.;

upstream raw materials:

6-amino-5-tetrahydropyran-2-yloxy-1H-pyrimidine-2,4-dione

Downstream raw materials:

5-hydroxybarbituric acid

Refernces

Isovioluric Acid (Alloxan-6-Oxime)

10.1073/pnas.18.7.490

The research investigates the chemical properties and transformations of isovioluric acid and its derivatives. The purpose of the study is to explore the behavior of isovioluric acid, an unusual oxime of alloxan, and its reduction products. Key chemicals involved include isovioluric acid (VI), which is derived from isobarbituric acid through the action of nitrous acid. This compound exhibits unique properties such as oxidation of potassium iodide and formation of colored salts. The study also examines the reduction of isovioluric acid to isouramil (XI) using ammonium sulfide, which resembles dialuric acid in its chemical properties and can be converted into dialuric acid (XII) by hydrochloric acid. The research concludes that isovioluric acid and its derivatives display distinct behaviors compared to related compounds like alloxan and violuric acid, providing new insights into the chemistry of these uracil derivatives and their potential applications in the study of purine group compounds.

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