2,6-diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile

Base Information

Chemical Name:2,6-diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile
CAS No.:208254-22-2
Molecular Formula:C13H9FN4S
Molecular Weight:272.30100
Hs Code.:
DSSTox Substance ID:DTXSID10353918
ChEMBL ID:CHEMBL4516025
Mol file:208254-22-2.mol

Synonyms:2,6-diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile;208254-22-2;CHEMBL4516025;Cambridge id 5212007;TimTec1_006498;SCHEMBL15572213;DTXSID10353918;HMS1552H08;BDBM50555901;STK860430;AKOS000551206;AB00075338-01;SR-01000510131;SR-01000510131-1;Z57075127

Suppliers and Price of 2,6-diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2,6-Diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile
1g
$ 1260.00

American Custom Chemicals Corporation
2,6-DIAMINO-4-(2-FLUOROPHENYL)-4H-THIOPYRAN-3,5-DICARBONITRILE 95.00%
5MG
$ 496.79

Total 1 raw suppliers

Chemical Property of 2,6-diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile

Chemical Property:

PSA：124.92000
LogP:3.44446
XLogP3:2.3
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:1
Exact Mass:272.05319564
Heavy Atom Count:19
Complexity:510

Purity/Quality:: 2,6-Diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C(=C1)C2C(=C(SC(=C2C#N)N)N)C#N)F
Uses 2,6-Diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile is an inhibitor of eEF-2 Kinase, which is a potential theraputic target for breast cancer, gliomas, and depression. 2,6-Diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile is also used as a reagent to synthesize substituted 3-aryl-2-(2-thiazolyl)acrylonitriles.

Technology Process of 2,6-diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile

There total 1 articles about 2,6-diamino-4-(2-fluorophenyl)-4H-thiopyran-3,5-dicarbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%