1H-Pyrazol-5-ol, 4,4'-[1,2-ethanediylbis(nitriloethylidyne)]bis[3-methyl-1-phenyl-

Base Information

• Chemical Name: 1H-Pyrazol-5-ol, 4,4'-[1,2-ethanediylbis(nitriloethylidyne)]bis[3-methyl-1-phenyl-
• CAS No.: 210769-44-1
• Molecular Formula: C₂₆H₂₈N₆O₂
• Molecular Weight: 456.547
• Mol file: 210769-44-1.mol

Synonyms:

Chemical Property of 1H-Pyrazol-5-ol, 4,4'-[1,2-ethanediylbis(nitriloethylidyne)]bis[3-methyl-1-phenyl-

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1H-Pyrazol-5-ol, 4,4'-[1,2-ethanediylbis(nitriloethylidyne)]bis[3-methyl-1-phenyl-

There total 1 articles about 1H-Pyrazol-5-ol, 4,4'-[1,2-ethanediylbis(nitriloethylidyne)]bis[3-methyl-1-phenyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

ethylenediamine (107-15-3,85404-18-8) + 1-phenyl-3-methyl-4-acetylpyrazol-5-one (37703-59-6) → Schiff base of 4-acetyl-1-phenyl-3-methyl-2-pyrazolin-5-one with ethylene diamine (210769-44-1)

Guidance literature:

In ethanol; for 1h; Heating;

Reference yield: 71.0%

chromium(III) nitrate nonahydrate + Schiff base of 4-acetyl-1-phenyl-3-methyl-2-pyrazolin-5-one with ethylene diamine (210769-44-1) → {((C3N2(CH3)(C6H5)(O)(C(CH3)N))2CH2CH2)Cr(H2O)2}(1+)*NO3(1-)={((C3N2(CH3)(C6H5)(O)(C(CH3)N))2CH2CH2)Cr(H2O)2}NO3

Guidance literature:

In ethanol; refluxing of ligand in ethanol (0.005mole in 150ml EtOH), addn. of a hot alc. Cr(NO3)3*9H2O soln. (0.005mole), addn. of sodium acetate (2g) and refluxing mixture (1h);; concg. to half the volume, filtration, washing and drying at 45°C; elem. anal.;;

Reference yield: 60.0%

nickel(II) nitrate hexahydrate + Schiff base of 4-acetyl-1-phenyl-3-methyl-2-pyrazolin-5-one with ethylene diamine (210769-44-1) → Ni((OCN(C6H5)NC(CH3)CC(CH3)N)2(CH2)2)(H2O)2

Guidance literature:

With sodium acetate; In ethanol; byproducts: HNO3, H2O; hot EtOH soln. of ligand (slight excess over 1 equiv.) added dropwise tohot EtOH soln. of Ni salt; NaOAc added under reflux; refluxed for 1 h; concd. to half of vol.; filtered; ppt. washed with hot water and hot EtOH; dried at 45°C; elem. anal.;

DOI:10.1081/SIM-120035951

upstream raw materials:

ethylenediamine

1-phenyl-3-methyl-4-acetylpyrazol-5-one