6-(Trifluoromethoxy)quinoline

Base Information

Chemical Name:6-(Trifluoromethoxy)quinoline
CAS No.:212695-45-9
Molecular Formula:C10H6F3NO
Molecular Weight:213.15600
Hs Code.:2933499090
DSSTox Substance ID:DTXSID10573992
Nikkaji Number:J2.434.165H
Wikidata:Q82462855
Mol file:212695-45-9.mol

Synonyms:6-(TRIFLUOROMETHOXY)QUINOLINE;212695-45-9;6-Trifluoromethoxy-quinoline;SCHEMBL2722588;DTXSID10573992;MFCD11855894;AKOS015852965;SB69999;BS-23412;CS-0080667;D74242;A879173

Suppliers and Price of 6-(Trifluoromethoxy)quinoline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
6-(trifluoromethoxy)quinoline
500mg
$ 220.00

Crysdot
6-(Trifluoromethoxy)quinoline 95+%
5g
$ 527.00

Chemenu
6-(Trifluoromethoxy)quinoline 95%
5g
$ 497.00

American Custom Chemicals Corporation
6-(TRIFLUOROMETHOXY)QUINOLINE 95.00%
5MG
$ 499.94

Alichem
6-(Trifluoromethoxy)quinoline
5g
$ 563.92

AK Scientific
6-(Trifluoromethoxy)quinoline
5g
$ 797.00

Total 14 raw suppliers

Chemical Property of 6-(Trifluoromethoxy)quinoline

Chemical Property:

PSA：22.12000
LogP:3.13340
Storage Temp.:2-8°C
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:213.04014830
Heavy Atom Count:15
Complexity:219

Purity/Quality:

97% ^*data from raw suppliers

6-(trifluoromethoxy)quinoline ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC2=C(C=CC(=C2)OC(F)(F)F)N=C1

Technology Process of 6-(Trifluoromethoxy)quinoline

There total 6 articles about 6-(Trifluoromethoxy)quinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 461-82-5
4-(trifluoromethoxy)aniline

: 127-68-4
sodium 3-nitrobenzenesulfonate

: 212695-45-9
6-(trifluoromethoxy)quinoline

Guidance literature:: With ferrous(II) sulfate heptahydrate; sulfuric acid; boric acid; In water; glycerol; at 0 - 150 ℃;

Reference yield: 39.0%

: C₁₁H₉NOS₂

: 212695-45-9
6-(trifluoromethoxy)quinoline

Guidance literature:: With trichloroisocyanuric acid; N-fluorobis(benzenesulfon)imide; In 1,2-dichloro-ethane; at 80 ℃; for 6h; Sealed tube;
DOI:10.1021/acs.joc.9b02717

Reference yield: 14.0%

: 6-(quinolinyl)tributylstannane

: 96898-10-1
tris(dimethylamino)sulfonium trifluoromethoxide

: 212695-45-9
6-(trifluoromethoxy)quinoline

Guidance literature:: tris(dimethylamino)sulfonium trifluoromethoxide; With trifluoromethyl trifluoromethanesulfonate; sodium hydrogencarbonate; In tetrahydrofuran; at -50 ℃; Inert atmosphere;

6-(quinolinyl)tributylstannane; With silver(I) hexafluorophosphate; 1-(chloromethyl)-4-fluoro-1,4-diazoniabicyclo[2.2.2]octane bis(hexafluorophosphate); In tetrahydrofuran; acetone; at -30 - 23 ℃; Inert atmosphere; Darkness;
DOI:10.1021/ja204861a