2,6-DIMETHOXY-P-XYLENE

Base Information

• Chemical Name: 2,6-DIMETHOXY-P-XYLENE
• CAS No.: 21390-25-0
• Molecular Formula: C10H14O2
• Molecular Weight: 166.22
• Mol file: 21390-25-0.mol

Synonyms:2,6-Dimethoxy-p-xylene;Benzene,1,3-dimethoxy-2,5-dimethyl;WT569;3,5-methoxy-4-methyltoluene;1,4-dimethyl-2,6-dimethoxybenzene;1,3-Dimethoxy-2,5-dimethylbenzol;

Chemical Property of 2,6-DIMETHOXY-P-XYLENE

Chemical Property:

• Vapor Pressure: 0.063mmHg at 25°C
• Boiling Point: 239.1oC at 760 mmHg
• Flash Point: 87.5oC
• PSA: 18.46000
• Density: 0.977g/cm3
• LogP: 2.32060
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

97% ^*data from raw suppliers

1,3-Dimethoxy-2,5-dimethylbenzene 95+% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2,6-DIMETHOXY-P-XYLENE

There total 4 articles about 2,6-DIMETHOXY-P-XYLENE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

1,3-dimethoxy-5-methylbenzene (4179-19-5) + methyl iodide (74-88-4) → 1,3-dimethoxy-2,5-dimethylbenzene (21390-25-0)

Guidance literature:

1,3-dimethoxy-5-methylbenzene; With n-butyllithium; In tetrahydrofuran;

methyl iodide;

DOI:10.1002/cmdc.201900548

Reference yield: 77.0%

methyl iodide (74-88-4) → 1,3-dimethoxy-2,5-dimethylbenzene (21390-25-0)

Guidance literature:

2,4,6-trimethoxytoluene; With potassium; In tetrahydrofuran; at 20 ℃; for 24h;

methyl iodide; In tetrahydrofuran; at 0 ℃; for 6h;

Reference yield:

3,4,5-trimethoxytoluene (6443-69-2) + methyl iodide (74-88-4) → 1,3-dimethoxy-2,5-dimethylbenzene (21390-25-0)

Guidance literature:

With potassium; Yield given. Multistep reaction; 1.) THF, rt, 24 h; 2.) 0 deg C, 4 h;

DOI:10.1016/S0040-4039(00)99555-8

upstream raw materials:

3,4,5-trimethoxytoluene

methyl iodide

1,3-dimethoxy-5-methylbenzene

Downstream raw materials:

1,3-dibromo-4,6-dimethoxy-2,5-dimethylbenzene

methyl 3,5-dimethoxy-4-methylbenzoate

2-methyl-5-phenethylbenzene-1,3-diol

5-(deuteriomethyl)-1,3-dimethoxy-2-methylbenzene