(2-Bromo-5-methoxy-4-methylphenyl)acetic acid

Base Information

Chemical Name:(2-Bromo-5-methoxy-4-methylphenyl)acetic acid
CAS No.:75097-32-4
Molecular Formula:C10H11BrO3
Molecular Weight:259.1
Hs Code.:
NSC Number:157016
DSSTox Substance ID:DTXSID30303157
Wikidata:Q82048307

Synonyms:75097-32-4;(2-bromo-5-methoxy-4-methylphenyl)acetic acid;2-(2-bromo-5-methoxy-4-methylphenyl)acetic acid;NSC157016;SCHEMBL1097015;DTXSID30303157;XIFCQXGNMPMNLU-UHFFFAOYSA-N;NSC-157016;(2-bromo-5-methoxy-4-methyl-phenyl)-acetic acid

Suppliers and Price of (2-Bromo-5-methoxy-4-methylphenyl)acetic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of (2-Bromo-5-methoxy-4-methylphenyl)acetic acid

Chemical Property:

Vapor Pressure:4.37E-06mmHg at 25°C
Boiling Point:368.7°Cat760mmHg
Flash Point:176.8°C
Density:1.494g/cm³
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:257.98916
Heavy Atom Count:14
Complexity:208

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC(=C(C=C1OC)CC(=O)O)Br

Technology Process of (2-Bromo-5-methoxy-4-methylphenyl)acetic acid

There total 6 articles about (2-Bromo-5-methoxy-4-methylphenyl)acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.4%

: 57335-02-1
2-bromo-5-methoxy-4-methylphenylacetonitrile

: 75097-32-4
2-bromo-5-methoxy-4-methylphenylacetic acid

Guidance literature:: With potassium hydroxide; water; for 36h; Heating;
DOI:10.1039/P19800001607

Reference yield: 77.0%

: 100861-38-9
(3-methoxy-4-methylphenyl)acetic acid

: 75097-32-4
2-bromo-5-methoxy-4-methylphenylacetic acid

Guidance literature:: With bromine; In acetic acid; at 20 ℃; for 3h; Inert atmosphere;

Reference yield:

: 57295-30-4
3-hydroxy-4-methylbenzaldehyde

: 75097-32-4
2-bromo-5-methoxy-4-methylphenylacetic acid

Guidance literature:: Multi-step reaction with 5 steps

1: 87 percent / aq. potassium hydroxide (33percent w/w)

2: 98.7 percent / sodium borohydride / methanol

3: 1.) thionyl chloride, 2.) sodium iodide, H₂O / 1.) benzene, 2.5 h, 2.) ethyl methyl ketone, reflux, 3 h

4: 65 percent / sodum acetate, bromine / CHCl₃ / 1 h / Ambient temperature

5: 98.4 percent / 0.85N methanolic potassium hydroxide, H₂O / 36 h / Heating

With potassium hydroxide; sodium tetrahydroborate; thionyl chloride; water; bromine; sodium acetate; sodium iodide; In methanol; chloroform;
DOI:10.1039/P19800001607