3-Methylcyclopentadecane-1,5-dione

Base Information

• Chemical Name: 3-Methylcyclopentadecane-1,5-dione
• CAS No.: 21890-10-8
• Molecular Formula: C16H28O2
• Molecular Weight: 252.397
• European Community (EC) Number: 606-859-3
• DSSTox Substance ID: DTXSID20458044
• Nikkaji Number: J2.435.101G
• Wikidata: Q82281170
• Mol file: 21890-10-8.mol

Synonyms:3-methylcyclopentadecane-1,5-dione;21890-10-8;EC 606-859-3;1,5-Cyclopentadecanedione, 3-methyl-;SCHEMBL727114;DTXSID20458044

Chemical Property of 3-Methylcyclopentadecane-1,5-dione

Chemical Property:

• Vapor Pressure: 3.49E-06mmHg at 25°C
• XLogP3: 4.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 252.208930132
• Heavy Atom Count: 18
• Complexity: 232

Purity/Quality:

99.9% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1CC(=O)CCCCCCCCCCC(=O)C1

Technology Process of 3-Methylcyclopentadecane-1,5-dione

There total 9 articles about 3-Methylcyclopentadecane-1,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(1RS,11RS,14RS)-1-hydroxy-14-methyl-bicyclo[9.4.0]pentadecan-12-one → 3-methylcyclopentadecane-1,5-dione (21890-10-8)

Guidance literature:

With sodium (+)-N-methylephedrine; In tetrahydrofuran; for 0.0166667h;

DOI:10.1002/anie.200604518

Reference yield: 95.0%

2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-2-methyl-1H-cyclopentacyclododecene (21890-09-5) → 3-methylcyclopentadecane-1,5-dione (21890-10-8)

Guidance literature:

With ruthenium trichloride; sodium hypochlorite; sodium hydroxide; In 1,2-dichloro-ethane; at 35 ℃; pH=7.9 - 14; Reagent/catalyst; Solvent;

Reference yield: 52.0%

3-methyl-1,5-dihydroxycyclopentadecane → 14-methyl-16-oxabicyclo[10.3.1]hexadec-1(15)-ene (73125-89-0) + 3-methylcyclopentadecane-1,5-dione (21890-10-8)

Guidance literature:

With Raney copper; at 50 - 200 ℃;

upstream raw materials:

t-14-Methyl-c-1,12-epoxybicyclo<10.3.0>pentadec-r-13-yl-(p-toluolsulfonat)

cis-u. trans-14-Methyl-c-1,12-epoxybicyclo<10.3.0>pentadec-r-13-yl-(p-toluolsulfonat)

2,3,4,5,6,7,8,9,10,11,12,13-dodecahydro-2-methyl-1H-cyclopentacyclododecene

14-methyl-6,17,18-trioxatricyclo[10.3.2.1^1,12 ]octadecane

Downstream raw materials:

14-methyl-16-oxabicyclo[10.3.1]hexadec-1⁽¹⁵⁾-ene

(3R,5Z)-3-methylcyclopentadec-5-enone

(-)-(R,E)-3-methyl-5-cyclopentadecen-1-one

(3S,5Z)-3-methylcyclopentadec-5-enone