N-(3,4-dichlorophenyl)-2-piperidin-1-ylacetamide

Base Information

Chemical Name:N-(3,4-dichlorophenyl)-2-piperidin-1-ylacetamide
CAS No.:22010-25-9
Molecular Formula:C₁₃H₁₆Cl₂N₂O
Molecular Weight:287.189
Hs Code.:
DSSTox Substance ID:DTXSID70877206
Nikkaji Number:J1.605.678B
Wikidata:Q82858957
Mol file:22010-25-9.mol

Synonyms:N-(3,4-dichlorophenyl)-2-piperidin-1-ylacetamide;22010-25-9;N-(3,4-dichlorophenyl)-2-(1-piperidinyl)acetamide;BAS 01377587;DTXSID70877206;AKOS000565032;AG-690/40696712;Z46157579;ACETAMIDE, N-(3,4-DICHLOROPHENYL)-2-(1-PIPERIDIN

Suppliers and Price of N-(3,4-dichlorophenyl)-2-piperidin-1-ylacetamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of N-(3,4-dichlorophenyl)-2-piperidin-1-ylacetamide

Chemical Property:

XLogP3:3.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:3
Exact Mass:286.0639685
Heavy Atom Count:18
Complexity:282

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1CCN(CC1)CC(=O)NC2=CC(=C(C=C2)Cl)Cl

Technology Process of N-(3,4-dichlorophenyl)-2-piperidin-1-ylacetamide

There total 3 articles about N-(3,4-dichlorophenyl)-2-piperidin-1-ylacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 110-89-4
piperidine

: 20149-84-2
2-chloro-N-(3,4-dichlorophenyl)acetamide

: 22010-25-9
piperidino-acetic acid-(3,4-dichloro-anilide)

Guidance literature:: In acetone; for 2h; Heating;
DOI:10.1007/BF00758665

Reference yield:

: 95-76-1
m,p-dichloroaniline

: 22010-25-9
piperidino-acetic acid-(3,4-dichloro-anilide)

Guidance literature:: Multi-step reaction with 2 steps

1: 98 percent / NaHCO₃ / dioxane / 0.5 h

2: 77 percent / acetone / 2 h / Heating

With sodium hydrogencarbonate; In 1,4-dioxane; acetone;
DOI:10.1007/BF00758665