Technology Process of Spiro[4.5]dec-6-en-2-one, 6,10-dimethyl-, (2,4-dinitrophenyl)hydrazone,
trans-
There total 37 articles about Spiro[4.5]dec-6-en-2-one, 6,10-dimethyl-, (2,4-dinitrophenyl)hydrazone,
trans- which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 13 steps
1: 22 g / diethyl ether
2: 72 percent / p-toluenesulfonic acid / benzene / 40 h / Heating
3: 6 g / potassium hydroxide, water / 3 h / Heating
4: oxalyl chloride, pyridine / benzene / 2 h / Ambient temperature
5: 1.5 g / diethyl ether
6: copper / benzene / 3.5 h / Heating
7: 86 percent / 1 N hydrochloric acid / tetrahydrofuran / 1.5 h / 65 °C
8: 80 percent / p-toluenesulfonic acid / benzene / 4 h / Heating
9: 83 percent / lithium tri-tert-butoxyaluminium hydride / diethyl ether / 18 h / Ambient temperature
10: 395 mg / pyridine / 5 h / Ambient temperature; in the dark
11: 45 percent / lithium, liq. ammonia / diethyl ether / 2 h
12: 41 percent / water, p-toluenesulfonic acid / acetone / 5 h / Ambient temperature
13: 43 mg
With
pyridine; hydrogenchloride; potassium hydroxide; oxalyl dichloride; lithium tri(t-butoxy)aluminum hydride; ammonia; water; lithium; copper; toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether; acetone; benzene;
- Guidance literature:
-
Multi-step reaction with 12 steps
1: 72 percent / p-toluenesulfonic acid / benzene / 40 h / Heating
2: 6 g / potassium hydroxide, water / 3 h / Heating
3: oxalyl chloride, pyridine / benzene / 2 h / Ambient temperature
4: 1.5 g / diethyl ether
5: copper / benzene / 3.5 h / Heating
6: 86 percent / 1 N hydrochloric acid / tetrahydrofuran / 1.5 h / 65 °C
7: 80 percent / p-toluenesulfonic acid / benzene / 4 h / Heating
8: 83 percent / lithium tri-tert-butoxyaluminium hydride / diethyl ether / 18 h / Ambient temperature
9: 395 mg / pyridine / 5 h / Ambient temperature; in the dark
10: 45 percent / lithium, liq. ammonia / diethyl ether / 2 h
11: 41 percent / water, p-toluenesulfonic acid / acetone / 5 h / Ambient temperature
12: 43 mg
With
pyridine; hydrogenchloride; potassium hydroxide; oxalyl dichloride; lithium tri(t-butoxy)aluminum hydride; ammonia; water; lithium; copper; toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether; acetone; benzene;
- Guidance literature:
-
Multi-step reaction with 9 steps
1: 1.5 g / diethyl ether
2: copper / benzene / 3.5 h / Heating
3: 86 percent / 1 N hydrochloric acid / tetrahydrofuran / 1.5 h / 65 °C
4: 80 percent / p-toluenesulfonic acid / benzene / 4 h / Heating
5: 83 percent / lithium tri-tert-butoxyaluminium hydride / diethyl ether / 18 h / Ambient temperature
6: 395 mg / pyridine / 5 h / Ambient temperature; in the dark
7: 45 percent / lithium, liq. ammonia / diethyl ether / 2 h
8: 41 percent / water, p-toluenesulfonic acid / acetone / 5 h / Ambient temperature
9: 43 mg
With
pyridine; hydrogenchloride; lithium tri(t-butoxy)aluminum hydride; ammonia; water; lithium; copper; toluene-4-sulfonic acid;
In
tetrahydrofuran; diethyl ether; acetone; benzene;
