76184-66-2

Upstream product

• 76184-65-1 2-(2,6-Dimethyl-4-oxo-cyclohex-2-enylmethyl)-malonic acid diethyl ester 

Downstream Products

• 22196-19-6 N-[(5S,10R)-6,10-Dimethyl-spiro[4.5]dec-6-en-(2E)-ylidene]-N'-(2,4-dinitro-phenyl)-hydrazine 
• 22196-19-6 N-[(5S,10S)-6,10-Dimethyl-spiro[4.5]dec-6-en-(2Z)-ylidene]-N'-(2,4-dinitro-phenyl)-hydrazine 
• 1460-73-7 (±)-agarospirol 

Relevant academic research and scientific papers

The total synthesis of (+/-)hinesol and (+/-)epihinesol

The tricyclic ketal ketones 15a and 15b have been obtained in an isomeric ratio of 9:1 (4 5 6 7 8 9 10 11 12 13 14 15a + 15b).Compound 15a was converted in seven (or eight) steps to (+/-)epihinesol (3) 29 32 48 49 47 (or 32 39 38 44 47) 50 3> and compound 38 was transformed into (+/-)hinesol (2) in five steps (38 76 77 62 63 2).The identity of epihinesol and agarospirol was confirmed by formation of a common epoxide.