3-(4-Chlorophenyl)isoindolin-1-one

Base Information

Chemical Name:3-(4-Chlorophenyl)isoindolin-1-one
CAS No.:2224-77-3
Molecular Formula:C14H10ClNO
Molecular Weight:243.692
Hs Code.:2933790090
European Community (EC) Number:636-573-4
UNII:Z4T4MYY7RG
Nikkaji Number:J3.191.275J
Mol file:2224-77-3.mol

Synonyms:2224-77-3;3-(4-Chlorophenyl)isoindolin-1-one;3-(4-chlorophenyl)-1-isoindolinone;1-(4-chlorophenyl)-3-oxoisoindoline;3-(4-chlorophenyl)-2,3-dihydroisoindol-1-one;3-(4-Chlorophenyl)-1-isoindolinone-d4;Z4T4MYY7RG;3-(4-chlorophenyl)-2,3-dihydro-1H-isoindol-1-one;SCHEMBL1444438;1H-Isoindol-1-one, 3-(4-chlorophenyl)-2,3-dihydro-;3-(4-Chlorophenyl)isoindolinone;3-(4-Chlorophenyl)phthalimidine;CAA22477;Phthalimidine, 3-(p-chlorophenyl)-;AKOS024324023;SB66000;F17324;3-(4-chlorophenyl)-2, 3-dihydroisoindol-1-one

Suppliers and Price of 3-(4-Chlorophenyl)isoindolin-1-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3-(4-Chlorophenyl)-1-isoindolinone
10mg
$ 55.00

Sigma-Aldrich
1-(4-CHLOROPHENYL)-3-OXOISOINDOLINE Aldrich
50mg
$ 144.00

American Custom Chemicals Corporation
1-(4-CHLOROPHENYL)-3-OXOISOINDOLINE 95.00%
5MG
$ 505.32

Alichem
1-(4-Chlorophenyl)-3-oxoisoindoline
100mg
$ 400.00

Total 19 raw suppliers

Chemical Property of 3-(4-Chlorophenyl)isoindolin-1-one

Chemical Property:

PSA：32.59000
LogP:3.18320
XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:243.0450916
Heavy Atom Count:17
Complexity:299

Purity/Quality:

99%, ^*data from raw suppliers

3-(4-Chlorophenyl)-1-isoindolinone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Canonical SMILES:C1=CC=C2C(=C1)C(NC2=O)C3=CC=C(C=C3)Cl
Uses 3-(4-Chlorophenyl)-1-isoindolinone is an intermediate of Chlorthalidone (C427500), a diuretic and antihypertensive agent.

Technology Process of 3-(4-Chlorophenyl)isoindolin-1-one

There total 10 articles about 3-(4-Chlorophenyl)isoindolin-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 2224-83-1
4-(4-chlorophenyl)-1H-2,3-benzoxazin-1-one

: 2224-77-3
3-(4'-chlorophenyl)-1-isoindolinone

Guidance literature:: With acetic acid; zinc; at 70 - 75 ℃;

Reference yield: 73.0%

: (4-chlorophenyl)(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)methanaminium chloride

: 7154-66-7
2-bromobenzoic acid chloride

: 2224-77-3
3-(4'-chlorophenyl)-1-isoindolinone

Guidance literature:: With [2,2]bipyridinyl; caesium carbonate; copper dichloride; In water; 1,2-dichloro-ethane; toluene; at 50 ℃; Inert atmosphere;
DOI:10.1021/acs.orglett.6b00586