Technology Process of Silane,
(1,1-dimethylethyl)[[(1S,6S)-1-[3-methoxy-2-(2-propenyl)phenyl]-6-[(tetra
hydro-2H-pyran-2-yl)oxy]-2-undecynyl]oxy]dimethyl-
There total 23 articles about Silane,
(1,1-dimethylethyl)[[(1S,6S)-1-[3-methoxy-2-(2-propenyl)phenyl]-6-[(tetra
hydro-2H-pyran-2-yl)oxy]-2-undecynyl]oxy]dimethyl- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
1H-imidazole; dmap;
In
dichloromethane; N,N-dimethyl-formamide;
at 20 ℃;
for 15h;
DOI:10.1021/jo0347720
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C
2: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C
3: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C
4: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C
With
1H-imidazole; dmap; dimethylsulfide; (R)-methyloxazaborolidine; borane; ethylmagnesium bromide; pyridinium chlorochromate;
In
tetrahydrofuran; diethyl ether; dichloromethane; N,N-dimethyl-formamide; toluene;
3: Corey reduction;
DOI:10.1021/jo0347720
- Guidance literature:
-
Multi-step reaction with 7 steps
1: TsOH*pyridine / CH2Cl2 / 15 h / 20 °C
2: BuLi / tetrahydrofuran; hexane / 15 h / 0 - 20 °C
3: NaOH / ethanol / 20 h / 20 °C
4: 92 percent / EtMgBr / tetrahydrofuran; diethyl ether / 0 - 20 °C
5: 75 percent / PCC / CH2Cl2 / 15 h / 0 - 20 °C
6: BH3; Me2S; (R)-methyloxazaborolidine / toluene; tetrahydrofuran / 1 h / -30 °C
7: 92 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide; CH2Cl2 / 15 h / 20 °C
With
1H-imidazole; dmap; sodium hydroxide; n-butyllithium; dimethylsulfide; (R)-methyloxazaborolidine; borane; ethylmagnesium bromide; pyridinium p-toluenesulfonate; pyridinium chlorochromate;
In
tetrahydrofuran; diethyl ether; ethanol; hexane; dichloromethane; N,N-dimethyl-formamide; toluene;
6: Corey reduction;
DOI:10.1021/jo0347720
