2-(2-METHOXYBENZOYL)BENZOIC ACID

Base Information

• Chemical Name: 2-(2-METHOXYBENZOYL)BENZOIC ACID
• CAS No.: 1151-04-8
• Molecular Formula: C15H12 O4
• Molecular Weight: 256.258
• Hs Code.: 2918990090
• Mol file: 1151-04-8.mol

Synonyms:Benzoicacid, o-(o-anisoyl)- (7CI,8CI); 2-(2-Methoxybenzoyl)benzoic acid; NSC 338406;o-(o-Methoxybenzoyl)benzoic acid

Chemical Property of 2-(2-METHOXYBENZOYL)BENZOIC ACID

Chemical Property:

• Vapor Pressure: 1.39E-10mmHg at 25°C
• Boiling Point: 494.2°Cat760mmHg
• Flash Point: 190.5°C
• PSA: 63.60000
• Density: 1.255g/cm³
• LogP: 2.62440

Purity/Quality:

98%,99%, ^*data from raw suppliers

2-(2-Methoxy-benzoyl)-benzoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(2-METHOXYBENZOYL)BENZOIC ACID

There total 12 articles about 2-(2-METHOXYBENZOYL)BENZOIC ACID which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

phthalic anhydride (85-44-9) + 2-bromoanisole (578-57-4) → 2-(2-methoxybenzoyl)benzoic acid (1151-04-8)

Guidance literature:

With n-butyllithium; In tetrahydrofuran; Cooling;

DOI:10.1021/ol3010694

Reference yield: 40.0%

Lithium o-Lithiobenzoate (57901-57-2) + 2-Methoxybenzoyl chloride (21615-34-9) → 2-(2-methoxybenzoyl)benzoic acid (1151-04-8)

Guidance literature:

In tetrahydrofuran; at -100 ℃; for 2h;

DOI:10.1021/jo00319a003

Reference yield:

phthalic anhydride (85-44-9) + 4-methoxyphenyl magnesium bromide (13139-86-1) → 2-(2-methoxybenzoyl)benzoic acid (1151-04-8) + 3,3-bis-(2-methoxy-phenyl)-phthalide (7477-27-2)

Guidance literature:

With diethyl ether; benzene;

DOI:10.1021/ja01261a504

upstream raw materials:

phthalic anhydride

4-methoxyphenyl magnesium bromide

2-hydroxybenzoylbenzoic acid

dimethyl sulfate

Downstream raw materials:

2-(2-methoxy-benzyl)-benzoic acid

methyl 2-(2-methoxybenzoyl)benzoate

p-N,N'-bis-BOC-guanidinophenyl 2-(2-methoxybenzoyl)benzoate