17-alpha-Mercaptoestra-1,3,5(10)-trien-3-ol

Base Information

Chemical Name:17-alpha-Mercaptoestra-1,3,5(10)-trien-3-ol
CAS No.:7438-72-4
Molecular Formula:C18H24OS
Molecular Weight:288.4476
Hs Code.:
NSC Number:524450,524449
DSSTox Substance ID:DTXSID60908311

Synonyms:NSC 524450;10329-87-0;17-alpha-Mercaptoestra-1,3,5(10)-trien-3-ol;C18H24OS;C18-H24-O-S;NSC-524450;NSC524449;DTXSID60908311;NSC524450;NSC-524449;LS-64799;17-Sulfanylestra-1(10),2,4-trien-3-ol;Estra-1,5(10)-trien-3-ol, 17-mercapto-, 17-alpha-

Suppliers and Price of 17-alpha-Mercaptoestra-1,3,5(10)-trien-3-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 17-alpha-Mercaptoestra-1,3,5(10)-trien-3-ol

Chemical Property:

Vapor Pressure:1.69E-08mmHg at 25°C
Boiling Point:444°Cat760mmHg
Flash Point:222.3°C
Density:1.18g/cm³
XLogP3:5
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:288.15478656
Heavy Atom Count:20
Complexity:384

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC12CCC3C(C1CCC2S)CCC4=C3C=CC(=C4)O

Technology Process of 17-alpha-Mercaptoestra-1,3,5(10)-trien-3-ol

There total 3 articles about 17-alpha-Mercaptoestra-1,3,5(10)-trien-3-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

: 14485-61-1
(8R,9S,13S,14S)-13-methyl-6,7,8,9,11,12,13,14,15,16-decahydrospiro[cyclopenta[a]phenanthrene-17,2'-[1,3]dithiolan]-3-ol

: 7438-72-4,10329-87-0
estrone-17-thiol

Guidance literature:: With n-butyllithium; In diethyl ether; at 25 ℃; for 6h;
DOI:10.1021/ja00530a043

Reference yield:

: 53-16-7
Estrone

: 7438-72-4,10329-87-0
estrone-17-thiol

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / p-toluenesulfonic acid / benzene / Heating

2: 93 percent / n-butyllithium / diethyl ether / 6 h / 25 °C

With n-butyllithium; toluene-4-sulfonic acid; In diethyl ether; benzene;
DOI:10.1021/ja00530a043