6-Chloro-n-(3-methoxyphenyl)nicotinamide

Base Information

Chemical Name:6-Chloro-n-(3-methoxyphenyl)nicotinamide
CAS No.:224817-08-7
Molecular Formula:C13H11ClN2O2
Molecular Weight:262.696
Hs Code.:
European Community (EC) Number:660-608-2
Mol file:224817-08-7.mol

Synonyms:6-chloro-n-(3-methoxyphenyl)nicotinamide;224817-08-7;SCHEMBL2303815;ASXCWGAHQLUQBZ-UHFFFAOYSA-N;AKOS000154227;DB-307091;6-chloro-N-(3-methoxy-phenyl)-nicotinamide

Suppliers and Price of 6-Chloro-n-(3-methoxyphenyl)nicotinamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 6-Chloro-n-(3-methoxyphenyl)nicotinamide

Chemical Property:

XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:262.0509053
Heavy Atom Count:18
Complexity:288

Purity/Quality:: 97% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=CC(=C1)NC(=O)C2=CN=C(C=C2)Cl

Technology Process of 6-Chloro-n-(3-methoxyphenyl)nicotinamide

There total 3 articles about 6-Chloro-n-(3-methoxyphenyl)nicotinamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 58757-38-3
6-Chloronicotinoyl chloride

: 536-90-3,918666-97-4
m-Anisidine

: 224817-08-7
6-chloro-N-(3-methoxy-phenyl)-nicotinamide

Guidance literature:: In dichloromethane; at 0 - 20 ℃; Reflux;

Reference yield: 75.0%

: 224817-08-7
6-chloro-N-(3-methoxy-phenyl)-nicotinamide

Guidance literature:

Reference yield:

: 5326-23-8
6-Chloro-3-pyridinecarboxylic acid

: 224817-08-7
6-chloro-N-(3-methoxy-phenyl)-nicotinamide

Guidance literature:: Multi-step reaction with 2 steps

1: dichloromethane / Reflux

2: triethylamine / dichloromethane / 20 °C

With triethylamine; In dichloromethane;
DOI:10.1021/jm3014103