Pyrrolidine, 1-[(4-methylphenyl)sulfonyl]-2-(2-oxopropyl)-

Base Information

Chemical Name:Pyrrolidine, 1-[(4-methylphenyl)sulfonyl]-2-(2-oxopropyl)-
CAS No.:227018-72-6
Molecular Formula:C14H19NO3S
Molecular Weight:281.376
Hs Code.:
DSSTox Substance ID:DTXSID00443514
Nikkaji Number:J1.099.483G
Mol file:227018-72-6.mol

Synonyms:227018-72-6;Pyrrolidine, 1-[(4-methylphenyl)sulfonyl]-2-(2-oxopropyl)-;DTXSID00443514;AKOS018102229;3-(1-Tosyl-2-pyrrolidinyl)-2-propanone

Suppliers and Price of Pyrrolidine, 1-[(4-methylphenyl)sulfonyl]-2-(2-oxopropyl)-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of Pyrrolidine, 1-[(4-methylphenyl)sulfonyl]-2-(2-oxopropyl)-

Chemical Property:

XLogP3:1.6
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:281.10856464
Heavy Atom Count:19
Complexity:419

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=CC=C(C=C1)S(=O)(=O)N2CCCC2CC(=O)C

Technology Process of Pyrrolidine, 1-[(4-methylphenyl)sulfonyl]-2-(2-oxopropyl)-

There total 10 articles about Pyrrolidine, 1-[(4-methylphenyl)sulfonyl]-2-(2-oxopropyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 70-55-3
toluene-4-sulfonamide

: 210349-18-1
(E)-7-iodo-3-hepten-2-one

: 227018-72-6
1-(1-(4-methylbenzenesulfonyl)-2-pyrrolidinyl)-2-propanone

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; for 24h; Ambient temperature;
DOI:10.1080/00397919908086214

Reference yield: 79.0%

: 1088669-92-4
C₁₄H₁₉NO₃S

: 227018-72-6
1-(1-(4-methylbenzenesulfonyl)-2-pyrrolidinyl)-2-propanone

Guidance literature:: C₁₄H₁₉NO₃S; With IndRu(PPh₃)2Cl; camphor-10-sulfonic acid; In tetrahydrofuran; at 20 ℃; for 0.0833333h; Inert atmosphere;

With indium(III) triflate; In tetrahydrofuran; for 1h; Reflux; Inert atmosphere;
DOI:10.1021/ja807696e