Benzoic acid, 4-(diphenylphosphinyl)-

Base Information

• Chemical Name: Benzoic acid, 4-(diphenylphosphinyl)-
• CAS No.: 2272-04-0
• Molecular Formula: C19H15O3P
• Molecular Weight: 322.3
• DSSTox Substance ID: DTXSID00406821
• Nikkaji Number: J1.834.453J
• Wikidata: Q82211927
• Mol file: 2272-04-0.mol

Synonyms:Benzoic acid, 4-(diphenylphosphinyl)-;2272-04-0;p-diphenylphosphinylbenzoic acid;SCHEMBL11497352;DTXSID00406821;4-(Diphenylphosphinoyl)benzoic acid

Chemical Property of Benzoic acid, 4-(diphenylphosphinyl)-

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 322.07588133
• Heavy Atom Count: 23
• Complexity: 420

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)P(=O)(C2=CC=CC=C2)C3=CC=C(C=C3)C(=O)O

Technology Process of Benzoic acid, 4-(diphenylphosphinyl)-

There total 22 articles about Benzoic acid, 4-(diphenylphosphinyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

4-iodobenzoic acid (619-58-9) + Diphenylphosphine oxide (4559-70-0) → diphenyl[(4-carboxy)phenyl]phosphine oxide (2272-04-0)

Guidance literature:

With palladium on activated charcoal; potassium carbonate; In water; at 100 ℃; for 1h; Reagent/catalyst; Temperature; Catalytic behavior; Green chemistry;

Reference yield: 97.0%

diphenyl(p-tolyl)phosphine (1031-93-2) → diphenyl[(4-carboxy)phenyl]phosphine oxide (2272-04-0)

Guidance literature:

With potassium permanganate; sodium hydroxide; In water; for 12h; Reflux;

DOI:10.1016/j.jfluchem.2012.09.001

Reference yield: 96.0%

4-diphenylphosphanobenzoic acid (2129-31-9) → diphenyl[(4-carboxy)phenyl]phosphine oxide (2272-04-0)

Guidance literature:

With pyridine; potassium permanganate; In water; for 21h; Reflux;

DOI:10.1002/anie.201809275

upstream raw materials:

diphenyl(p-tolyl)phosphine

p-tolyldichlorophosphine

4-iodobenzoic acid

Diphenylphosphine oxide

Downstream raw materials:

4-diphenylphosphanobenzoic acid

[4-diphenylphosphinyl]benzoyl chloride

1,4-bis(p-nitrostyryl)benzene

(4-(ethoxycarbonyl)phenyl)diphenylphosphine oxide