Phosphonous dichloride, (4-methylphenyl)-

Base Information

• Chemical Name: Phosphonous dichloride, (4-methylphenyl)-
• CAS No.: 1005-32-9
• Molecular Formula: C7H7 Cl2 P
• Molecular Weight: 193.012
• DSSTox Substance ID: DTXSID1074335
• Nikkaji Number: J1.455.080A
• Wikidata: Q82002710
• Mol file: 1005-32-9.mol

Synonyms:1005-32-9;Phosphonous dichloride, (4-methylphenyl)-;Phosphonous dichloride, P-(4-methylphenyl)-;p-Tolyldichlorophosphine;SCHEMBL2367541;DTXSID1074335

Chemical Property of Phosphonous dichloride, (4-methylphenyl)-

Chemical Property:

• Vapor Pressure: 0.0493mmHg at 25°C
• Boiling Point: 243.7°Cat760mmHg
• Flash Point: 101.2°C
• Density: g/cm³
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 0
• Exact Mass: 191.9662426
• Heavy Atom Count: 10
• Complexity: 97.8

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC=C(C=C1)P(Cl)Cl
• General Description: (4-Methylphenyl)phosphonous dichloride, also known as p-tolyldichlorophosphine or dichloro-p-tolylphosphine, is an organophosphorus compound characterized by a phosphorus center bonded to two chlorine atoms and a 4-methylphenyl (p-tolyl) group. It serves as a versatile intermediate in organic synthesis, particularly in the preparation of phosphonates, phosphinates, and other phosphorus-containing derivatives. (4-methylphenyl)phosphonous dichloride is reactive toward nucleophiles due to the presence of the P-Cl bonds, enabling its use in phosphorylation reactions and as a precursor for ligands in coordination chemistry. Its stability and reactivity make it valuable in the development of agrochemicals, pharmaceuticals, and materials science applications.

Technology Process of Phosphonous dichloride, (4-methylphenyl)-

There total 14 articles about Phosphonous dichloride, (4-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

p-tolylphosphonic dichloride (17566-84-6) → p-tolyldichlorophosphine (1005-32-9)

Guidance literature:

With triphenylphosphine;

Reference yield: 96.0%

toluene (108-88-3,15644-74-3,16713-13-6) → p-tolyldichlorophosphine (1005-32-9)

Guidance literature:

With aluminium trichloride; phosphorus trichloride; for 3h; Heating;

DOI:10.1016/S0040-4020(98)00601-2

Reference yield: 50.0%

Tri(p-tolyl)phosphine (1038-95-5,218281-19-7) → p-tolyldichlorophosphine (1005-32-9)

Guidance literature:

With phosphorus trichloride; at 300 ℃; for 5h;

upstream raw materials:

tetrachloro-p-tolylphosphorane

bis(p-tolyl)mercury

toluene

methyl-4-methylphenyl-dichlorosilane

Downstream raw materials:

p-tolylphosphinic acid

chloro-phenyl-p-tolyl-phosphine

di(n-butyl)(p-tolyl)phosphine

-kohlensaeure-aethylester