N,N'-dimethyl-1,2-diphenylethane-1,2-diamine

Base Information

• Chemical Name: N,N'-dimethyl-1,2-diphenylethane-1,2-diamine
• CAS No.: 22751-68-4
• Molecular Formula: C16H20N2
• Molecular Weight: 240.348
• European Community (EC) Number: 684-729-5
• DSSTox Substance ID: DTXSID90484390
• Nikkaji Number: J1.380.207F
• Mol file: 22751-68-4.mol

Synonyms:N,N'-dimethyl-1,2-diphenylethane-1,2-diamine;22751-68-4;(1S,2S)-N,N'-DIMETHYL-1,2-DIPHENYL-1,2-ETHYLENEDIAMINE;MFCD00216955;SCHEMBL5475480;DTXSID90484390;BCP30043;SY067021;n,n'-dimethyl-1,2-diphenylethylenediamine;FT-0660469;FT-0660470;methyl-(2-methylamino-1,2-diphenyl-ethyl)-amine;(1R,2R)-N1,N2-Dimethyl-1,2-diphenyl-1,2-ethanediamine;Methyl-[(1R,2R)-2-Methylammonio-1,2-Di(Phenyl)Ethyl]Ammonium;(1R,2R)-N,N'-Dimethyl-1,2-diphenylethylenediamine

Chemical Property of N,N'-dimethyl-1,2-diphenylethane-1,2-diamine

Chemical Property:

• PSA: 24.06000
• LogP: 3.68960
• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 5
• Exact Mass: 240.162648646
• Heavy Atom Count: 18
• Complexity: 193

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC(C1=CC=CC=C1)C(C2=CC=CC=C2)NC

Technology Process of N,N'-dimethyl-1,2-diphenylethane-1,2-diamine

There total 32 articles about N,N'-dimethyl-1,2-diphenylethane-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N-((1S,2S)-2-Formylamino-1,2-diphenyl-ethyl)-formamide (220665-71-4) → (S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine (22751-68-4,60508-97-6,60509-62-8,70749-06-3,118628-68-5)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran; Heating;

DOI:10.1021/jo9820723

Reference yield: 89.0%

(R,S)-N,N'-dimethyl-1,2-diphenylethylenediamine (60509-62-8,1219814-39-7) → (+/-)-N,N'-dimethyl-1,2-diphenyl-1,2-ethylenediamine (22751-68-4,60508-97-6,60509-62-8,70749-06-3,118628-68-5) + benzyl-methyl-amine (103-67-3)

Guidance literature:

With lithium; isoprene; In tetrahydrofuran; at 35 ℃; for 1h; Yields of byproduct given;

DOI:10.1055/s-1998-1791

Reference yield: 84.0%

(S3,S4)-1-phenyl-N,N'-dimethyl-(3,4-diphenyl)diazaphospholidine 1-oxide → (S,S)-N,N'-dimethyl-1,2-diphenylethane-1,2-diamine (22751-68-4,60508-97-6,60509-62-8,70749-06-3,118628-68-5)

Guidance literature:

hydrogenchloride; In methanol; Heating;

DOI:10.1016/S0040-4039(01)02054-8

upstream raw materials:

N-Benzylidenemethylamine

Tetramethyltetrazon

benzyl alcohol

N-benzylidenemethylamine

Downstream raw materials:

1,3-dimethyl-4,5-diphenylimidazolidine

rac-1,3-dimethyl-4,5-diphenylimidazolidine

1,3-dimethyl-r-2,c-4,t-5-triphenylimidazolidine

C₂₅H₃₆N₂O₄S₂