3-(1-Methyl-2-pyrrolidinyl)indole

Base Information

Chemical Name:3-(1-Methyl-2-pyrrolidinyl)indole
CAS No.:7236-83-1
Molecular Formula:C₁₃H₁₆N₂
Molecular Weight:200.283
Hs Code.:
UNII:254KT5K2BQ
DSSTox Substance ID:DTXSID50993150
Nikkaji Number:J41.068C
Mol file:7236-83-1.mol

Synonyms:3-(1-Methyl-2-pyrrolidinyl)indole;BRN 0611673;INDOLE, 3-(1-METHYL-2-PYRROLIDINYL)-;7236-83-1;254KT5K2BQ;3-(1-Methyl-2-pyrrolidinyl)-1H-indole;1H-Indole, 3-(1-methyl-2-pyrrolidinyl)-;5-23-07-00373 (Beilstein Handbook Reference);3-(1-methylpyrrolidin-2-yl)-1H-indole;UNII-254KT5K2BQ;Oprea1_713525;SCHEMBL13162093;DTXSID50993150;3-(1-methyl-2-pyrrolidyl)indole;LS-83297

Suppliers and Price of 3-(1-Methyl-2-pyrrolidinyl)indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
3-(1-METHYL-2-PYRROLIDINYL)-1H-INDOLE 95.00%
5MG
$ 500.81

Total 5 raw suppliers

Chemical Property of 3-(1-Methyl-2-pyrrolidinyl)indole

Chemical Property:

Vapor Pressure:4.37E-05mmHg at 25°C
Refractive Index:1.5014 (estimate)
Boiling Point:350.5°Cat760mmHg
Flash Point:165.8°C
PSA：19.03000
Density:1.135g/cm³
LogP:2.87250
XLogP3:2.4
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:200.131348519
Heavy Atom Count:15
Complexity:229

Purity/Quality:

99% ^*data from raw suppliers

3-(1-METHYL-2-PYRROLIDINYL)-1H-INDOLE 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCCC1C2=CNC3=CC=CC=C32

Technology Process of 3-(1-Methyl-2-pyrrolidinyl)indole

There total 4 articles about 3-(1-Methyl-2-pyrrolidinyl)indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 83.0%

: 4631-10-1
(Z)-3-(1-methylpyrrolidin-2-ylidene)-3H-indole

: 7236-83-1
3-(1-methylpyrrolidin-2-yl)-1H-indole

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; for 6h; Reflux;
DOI:10.1021/acs.jmedchem.8b01936

Reference yield:

: 872-50-4,26138-58-9
1-methyl-pyrrolidin-2-one

: 7236-83-1
3-(1-methylpyrrolidin-2-yl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / 0.08 h / 0 °C

1.2: 2 h / 0 - 80 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 6 h / Reflux

With lithium aluminium tetrahydride; trichlorophosphate; In tetrahydrofuran;
DOI:10.1021/acs.jmedchem.8b01936

Reference yield:

: 120-72-9
indole

: 7236-83-1
3-(1-methylpyrrolidin-2-yl)-1H-indole

Guidance literature:: Multi-step reaction with 2 steps

1.1: trichlorophosphate / 0.08 h / 0 °C

1.2: 2 h / 0 - 80 °C

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 6 h / Reflux

With lithium aluminium tetrahydride; trichlorophosphate; In tetrahydrofuran;
DOI:10.1021/acs.jmedchem.8b01936