2,3,8,9-Tetramethoxybenzo(c)phenanthridine

Base Information

• Chemical Name: 2,3,8,9-Tetramethoxybenzo(c)phenanthridine
• CAS No.: 15462-10-9
• Molecular Formula: C₂₁H₁₉NO₄
• Molecular Weight: 349.386
• NSC Number: 166717
• DSSTox Substance ID: DTXSID20165680
• Nikkaji Number: J3.238.975I
• Wikidata: Q83034909
• ChEMBL ID: CHEMBL520793
• Mol file: 15462-10-9.mol

Synonyms:15462-10-9;2,3,8,9-Tetramethoxybenzo(c)phenanthridine;NSC166717;NSC 166717;2,3,8,9-Tetramethoxybenzo[c]phenanthridine;CHEMBL520793;DTXSID20165680;NSC-166717;2,3,8,9-tetramethoxy-benzo[c]phenanthridine

Chemical Property of 2,3,8,9-Tetramethoxybenzo(c)phenanthridine

Chemical Property:

• Vapor Pressure: 2.66E-11mmHg at 25°C
• Boiling Point: 543°Cat760mmHg
• Flash Point: 190.8°C
• Density: 1.243g/cm³
• XLogP3: 4.6
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 4
• Exact Mass: 349.13140809
• Heavy Atom Count: 26
• Complexity: 475

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C=C2C(=C1)C=CC3=C2N=CC4=CC(=C(C=C34)OC)OC)OC

Technology Process of 2,3,8,9-Tetramethoxybenzo(c)phenanthridine

There total 26 articles about 2,3,8,9-Tetramethoxybenzo(c)phenanthridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

O-methylfagaronine iodide (136540-26-6) → 2,3,8,9-tetramethoxybenzophenanthridine (15462-10-9)

Guidance literature:

at 308 - 310 ℃; for 0.0833333h;

Reference yield: 88.0%

C21H21NO4 → 2,3,8,9-tetramethoxybenzophenanthridine (15462-10-9)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,4-dioxane; at 20 ℃; for 12h; Inert atmosphere;

DOI:10.1021/acs.joc.1c01612

Reference yield: 82.0%

N-formyl-2-(3,4-dimethoxyphenyl)-6,7-dimethoxynaphthalen-1-amine (102475-27-4) → 2,3,8,9-tetramethoxybenzophenanthridine (15462-10-9)

Guidance literature:

With trichlorophosphate; In acetonitrile; for 3h; Reflux;

DOI:10.1016/j.tet.2010.10.035

upstream raw materials:

N-formyl-2-(3,4-dimethoxyphenyl)-6,7-dimethoxynaphthalen-1-amine

2,3,8,9-tetramethoxy-4b,10b,11,12-tetrahydro-benzo[c]phenanthridine

2,3,8,9-Tetramethoxy-12-(1-phenyl-1H-tetrazol-5-yloxy)benzophenanthridine

O-methylfagaronine iodide

Downstream raw materials:

5H-2,3,8,9-tetramethoxybenzophenanthridinium tosylate

5-methyl-2,3,8,9-tetramethoxybenzophenanthridinium tosylate

2,3,8,9-tetramethoxy-5-methyl-benzo[c]phenanthridinium; methyl sulfate